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下颌追踪技术对小射野容积调强放疗计划剂量计算准确性的影响。

Influence of the jaw tracking technique on the dose calculation accuracy of small field VMAT plans.

作者信息

Swinnen Ans C C, Öllers Michel C, Roijen Erik, Nijsten Sebastiaan M, Verhaegen Frank

机构信息

Radiotherapy Department, Maastro Clinic, 6229 ET, Maastricht, The Netherlands.

出版信息

J Appl Clin Med Phys. 2017 Jan;18(1):186-195. doi: 10.1002/acm2.12029. Epub 2017 Jan 3.

Abstract

PURPOSE

The aim of this study was to evaluate experimentally the accuracy of the dose calculation algorithm AcurosXB in small field highly modulated Volumetric Modulated Arc Therapy (VMAT).

METHOD

The 1000SRS detector array inserted in the rotational Octavius 4D phantom (PTW) was used for 3D dose verification of VMAT treatments characterized by small to very small targets. Clinical treatment plans (n = 28) were recalculated on the phantom CT data set in the Eclipse TPS. All measurements were done on a Varian TrueBeamSTx, which can provide the jaw tracking technique (JTT). The effect of disabling the JTT, thereby fixing the jaws at static field size of 3 × 3 cm and applying the MLC to shape the smallest apertures, was investigated for static fields between 0.5 × 0.5-3 × 3 cm and for seven VMAT patients with small brain metastases. The dose calculation accuracy has been evaluated by comparing the measured and calculated dose outputs and dose distributions. The dosimetric agreement has been presented by a local gamma evaluation criterion of 2%/2 mm.

RESULTS

Regarding the clinical plans, the mean ± SD of the volumetric gamma evaluation scores considering the dose levels for evaluation of 10%, 50%, 80% and 95% are (96.0 ± 6.9)%, (95.2 ± 6.8)%, (86.7 ± 14.8)% and (56.3 ± 42.3)% respectively. For the smallest field VMAT treatments, discrepancies between calculated and measured doses up to 16% are obtained. The difference between the 1000SRS central chamber measurements compared to the calculated dose outputs for static fields 3 × 3, 2 × 2, 1 × 1 and 0.5 × 0.5 cm collimated with MLC whereby jaws are fixed at 3 × 3 cm and for static fields shaped with the collimator jaws only (MLC retracted), is on average respectively, 0.2%, 0.8%, 6.8%, 5.7% (6 MV) and 0.1%, 1.3%, 11.7%, 21.6% (10 MV). For the seven brain mets patients was found that the smaller the target volumes, the higher the improvement in agreement between measured and calculated doses after disabling the JTT.

CONCLUSION

Fixing the jaws at 3 × 3 cm and using the MLC with high positional accuracy to shape the smallest apertures in contrast to the JTT is currently found to be the most accurate treatment technique.

摘要

目的

本研究旨在通过实验评估小射野高调制容积调强弧形治疗(VMAT)中剂量计算算法AcurosXB的准确性。

方法

将插入旋转式Octavius 4D体模(PTW)中的1000SRS探测器阵列用于对具有小至极小靶区的VMAT治疗进行三维剂量验证。在Eclipse治疗计划系统中,根据体模CT数据集重新计算临床治疗计划(n = 28)。所有测量均在能提供颌部跟踪技术(JTT)的Varian TrueBeamSTx直线加速器上进行。研究了禁用JTT的效果,即将颌部固定在3×3 cm的静态射野尺寸,并应用多叶准直器(MLC)形成最小孔径,对0.5×0.5 - 3×3 cm的静态射野以及7例患有小脑转移瘤的VMAT患者进行了研究。通过比较测量和计算的剂量输出及剂量分布来评估剂量计算准确性。剂量学一致性通过2%/2 mm的局部γ评估标准来表示。

结果

对于临床计划,考虑10%、50%、80%和95%剂量水平进行评估时,容积γ评估分数的平均值±标准差分别为(96.0 ± 6.9)%、(95.2 ± 6.8)%、(86.7 ± 14.8)%和(56.3 ± 42.3)%。对于最小射野的VMAT治疗,计算剂量与测量剂量之间的差异高达16%。1000SRS中央腔室测量值与计算剂量输出值之间的差异,对于用MLC准直且颌部固定在3×3 cm的3×3、2×2、1×1和0.5×0.5 cm静态射野以及仅用准直器颌部塑形(MLC收起)的静态射野,平均分别为0.2%、0.8%、6.8%、5.7%(6 MV)和0.1%、1.3%、11.7%、21.6%(10 MV)。对于7例脑转移瘤患者,发现靶区体积越小,则禁用JTT后测量剂量与计算剂量之间的一致性改善越高。

结论

与JTT相比,将颌部固定在3×3 cm并使用具有高位置精度的MLC来形成最小孔径目前被认为是最准确的治疗技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c0/5689875/9139b3770894/ACM2-18-186-g001.jpg

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