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成人院前复苏规则在儿童院外心脏骤停中的应用。

Application of adult prehospital resuscitation rules to pediatric out of hospital cardiac arrest.

作者信息

Matsui Satoshi, Kitamura Tetsuhisa, Kurosawa Hiroshi, Kiyohara Kosuke, Tanaka Ryojiro, Sobue Tomotaka, Nitta Masahiko

机构信息

Division of Environmental Medicine and Population Sciences, Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, Osaka, Japan; Division of Emergency Medicine, Hyogo Prefectural Kobe Children's Hospital, Kobe, Japan.

Division of Environmental Medicine and Population Sciences, Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.

出版信息

Resuscitation. 2023 Mar;184:109684. doi: 10.1016/j.resuscitation.2022.109684. Epub 2022 Dec 28.

Abstract

BACKGROUND

Prehospital termination of resuscitation (TOR) rules can be recommended for adults with out-of-hospital cardiac arrests (OHCAs). This study aimed to investigate whether adult basic life support (BLS) and advanced life support (ALS) TOR rules can predict neurologically unfavorable one-month outcome for pediatric OHCA patients.

METHODS

From a nationwide population-based observational cohort study, we extracted data of consecutive pediatric OHCA patients (0-17 years old) from January 1, 2005, to December 31, 2011. The BLS TOR rule has three criteria, whereas the ALS TOR rule includes two additional criteria. We selected pediatric OHCA patients that met all criteria for each TOR rule and calculated the specificity and positive predictive value (PPV) of each TOR rule for identifying pediatric OHCA patients who did not have neurologically favorable one-month outcome.

RESULTS

Of the 12,740 pediatric OHCA patients eligible for the evaluation of the BLS TOR rule, 10,803 patients met the BLS TOR rule, with a specificity of 0.785 and a PPV of 0.987 for predicting a lack of neurologically favorable one-month survival. Of the 2,091 for the ALS TOR rule, 381 patients met the ALS TOR rule, with a specificity of 0.986 and a PPV of 0.997 for predicting neurologically unfavorable one-month outcome.

CONCLUSIONS

The adult BLS and ALS TOR rules had a high PPV for predicting pediatric OHCA patients without a neurologically favorable survival at one month after onset.

摘要

背景

对于院外心脏骤停(OHCA)的成人患者,可以推荐使用院前复苏终止(TOR)规则。本研究旨在调查成人基础生命支持(BLS)和高级生命支持(ALS)的TOR规则能否预测小儿OHCA患者1个月时神经功能不良的结局。

方法

从一项全国性基于人群的观察性队列研究中,我们提取了2005年1月1日至2011年12月31日期间连续的小儿OHCA患者(0 - 17岁)的数据。BLS的TOR规则有三个标准,而ALS的TOR规则还包括另外两个标准。我们选择符合每个TOR规则所有标准的小儿OHCA患者,并计算每个TOR规则用于识别1个月时神经功能不良结局的小儿OHCA患者的特异性和阳性预测值(PPV)。

结果

在12740例符合BLS的TOR规则评估条件的小儿OHCA患者中,10803例患者符合BLS的TOR规则,预测1个月时缺乏神经功能良好生存的特异性为0.785,PPV为0.987。在2091例符合ALS的TOR规则评估条件的患者中,381例患者符合ALS的TOR规则,预测1个月时神经功能不良结局的特异性为0.986,PPV为0.997。

结论

成人BLS和ALS的TOR规则对于预测发病后1个月时神经功能未良好存活的小儿OHCA患者具有较高的PPV。

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