Anokhin B M, Propp R M, Romanova L F
Probl Endokrinol (Mosk). 1987 May-Jun;33(3):3-6.
The levels of TSH, T4, T3, calcitonin (CT), PTH, TGA and TG were determined in 96 persons (87 patients and 9 healthy persons) before and after operation; 46 patients had papillary carcinoma, 15 follicular cancer, 24 medullary carcinoma, 2 undifferentiated cancer. There was no common clinicomorphological approach to the studied problem therefore it was impossible to compare the data of different researchers. Radionuclide tests were employed to specify the importance of different methods in clinical practice. Elevated levels of TG, TSH, PTH, T4 and a lowered level of CT were revealed in differentiated thyroid carcinomas; elevated levels of CT, TSH, PTH, T4 and a lowered level of TG were revealed in medullary carcinoma. A decrease in T4 and T3 levels was noted after operations in patients with differentiated thyroid cancers necessitating the use of substitution therapy and thyroid hormones.
对96人（87例患者和9名健康人）在手术前后测定了促甲状腺激素（TSH）、甲状腺素（T4）、三碘甲状腺原氨酸（T3）、降钙素（CT）、甲状旁腺激素（PTH）、甲状腺球蛋白抗体（TGA）和甲状腺球蛋白（TG）的水平；46例患者为乳头状癌，15例为滤泡状癌，24例为髓样癌，2例为未分化癌。对于所研究的问题，没有通用的临床形态学方法，因此无法比较不同研究者的数据。采用放射性核素检查来明确不同方法在临床实践中的重要性。在分化型甲状腺癌中发现TG、TSH、PTH、T4水平升高，CT水平降低；在髓样癌中发现CT、TSH、PTH、T4水平升高，TG水平降低。分化型甲状腺癌患者术后T4和T3水平下降，需要使用替代疗法和甲状腺激素。
