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表现为多灶性粉红色病变的结膜无黑色素性黑色素瘤。

Conjunctival amelanotic melanoma presenting as a multifocal pink lesion.

机构信息

Ophthalmology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia

School of Medicine, Deakin University-Geelong Waurn Ponds Campus, Geelong, Victoria, Australia.

出版信息

BMJ Case Rep. 2022 Dec 7;15(12):e250682. doi: 10.1136/bcr-2022-250682.

Abstract

Conjunctival amelanotic malignant melanoma is a rare form of melanoma, which lacks visible pigment and is commonly located underneath the eyelids in the bulbar conjunctiva. In this report, we described a case of a Caucasian women in her 70s who presented with unilateral irritation and tenderness following cataract surgery. On eversion of the eyelid, two elevated pink lesions were noted. Tumour - Node - Metastasis staging with the American Joint Committee on Cancer staging system eighth edition was T3C and required multiple excisions and reconstruction procedures. This case exemplified the diagnostic pitfall of conjunctival amelanotic malignant melanoma, which is a potentially life-threatening disease and the importance of histopathology in the diagnostic process.

摘要

结膜无色素性恶性黑色素瘤是一种罕见的黑色素瘤,它缺乏可见的色素,通常位于眼睑下方的球结膜内。在本报告中,我们描述了一位 70 多岁的白人女性的病例,她在白内障手术后出现单侧刺激和压痛。当翻转眼睑时,发现两个隆起的粉红色病变。根据美国癌症联合委员会分期系统第八版的肿瘤-淋巴结-转移分期(TNM 分期)为 T3C,需要多次切除和重建手术。本例说明了结膜无色素性恶性黑色素瘤的诊断陷阱,这是一种潜在危及生命的疾病,组织病理学在诊断过程中的重要性。

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本文引用的文献

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4
Conjunctival Melanoma - Epidemiological Trends and Features.
Pathol Oncol Res. 2018 Oct;24(4):787-796. doi: 10.1007/s12253-018-0419-3. Epub 2018 May 25.
5
Lack of tumour pigmentation in conjunctival melanoma is associated with light iris colour and worse prognosis.
Br J Ophthalmol. 2019 Mar;103(3):332-337. doi: 10.1136/bjophthalmol-2018-312018. Epub 2018 May 18.
6
Pembrolizumab for Recurrent Conjunctival Melanoma.
JAMA Ophthalmol. 2017 Aug 1;135(8):891-892. doi: 10.1001/jamaophthalmol.2017.2279.
8
Conjunctival Lymphoma--An International Multicenter Retrospective Study.
JAMA Ophthalmol. 2016 Apr;134(4):406-14. doi: 10.1001/jamaophthalmol.2015.6122.
9
Management of conjunctival malignant melanoma: a review and update.
Expert Rev Ophthalmol. 2014 Jun;9(3):185-204. doi: 10.1586/17469899.2014.921119.
10
Conjunctival melanoma and melanocytic intra-epithelial neoplasia.
Eye (Lond). 2013 Feb;27(2):142-52. doi: 10.1038/eye.2012.254. Epub 2012 Dec 7.

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