基于早期生命重编程的治疗方法可促进长寿。
Early Life Reprogramming-Based Treatment Promotes Longevity.
机构信息
Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, Texas, USA.
Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas, USA.
出版信息
Cell Reprogram. 2023 Feb;25(1):9-10. doi: 10.1089/cell.2022.0153. Epub 2022 Dec 30.
PMID:36594927
Abstract
Short-term expression of Yamanaka factors early in life promotes epigenetic reprogramming and an increased healthy lifespan in a mouse model of accelerated aging.
摘要
在生命早期短期表达 Yamanaka 因子可促进表观遗传重编程，并延长加速衰老小鼠模型的健康寿命。
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