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与无菌性翻修全膝关节置换术相比,感染性伸肌机制同种异体移植重建术后长期随访结果较差。

Inferior results at long-term follow-up after extensor mechanism allograft reconstruction in septic compared to aseptic revision total knee arthroplasty.

作者信息

Baldini Andrea, Lamberti Alfredo, Balato Giovanni, Cavallo Giuseppe, Summa Pierpaolo

机构信息

Istituto Fiorentino di Cura e Assistenza (IFCA), Via del Pergolino 4/6, 50139, Florence, Italy.

Department of Public Health, School of Medicine, Federico II University, Via S. Pansini, 80131, Naples, Italy.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2023 Apr;31(4):1477-1482. doi: 10.1007/s00167-022-07280-0. Epub 2023 Jan 3.

DOI:10.1007/s00167-022-07280-0
PMID:36595053
Abstract

PURPOSE

Extensor mechanism lesion after total knee arthroplasty (TKA) is a catastrophic complication. Reconstruction with extensor mechanism allograft (EMA) has been described as a sound salvage procedure. Its effectiveness at long term and in septic cases is still under scrutiny. The long-term results of EMA reconstruction for chronic extensor mechanism failures following aseptic and septic revision TKA have been analysed.

METHODS

From the institutional database, 35 patients with a revision TKA (RevTKA) undergoing EMA reconstruction from 2005 to 2015 have been retrospectively identified. A history of periprosthetic joint infection (PJI) was found in 13 (37%) patients. The mean follow-up was 81.2 months (± 34.7, range 3-120). EMA failures were considered for lag more than 20°, Knee Society Score (KSS) less than 60 points, and/or in the case of revision of the allograft.

RESULTS

The mean KSS improved from 35.9 (± 16.9, range 0-54) to 86.6 (± 10.4, range 54-99) points in the aseptic group (p < 0.001) and from 27.5 (± 11.6, range 10-44) to 79.4 (± 16.3, range 48-94) points in the septic group (p < 0.001). The extensor lag changed from 48.4° (± 14.5, range 30-90) to 4.6° (± 10.8, range 0-50) in the aseptic group (p < 0.001) and from 56.5° (± 20.8, range 30-90) to 6.1° (± 6.8, range 0-20) in the septic group (p < 0.001). The mean postoperative flexion was 105.2° (± 13.2, range 75-130) in the aseptic group and 102.7° (± 12.5, range 80-120) in the septic group (p = 0.32). Three failures (14% of the cases) occurred in the aseptic group and five in the septic group (38% of the cases). The overall survivorship at 10 years was 83.3% (22 cases, CI 94.2-121.7) vs 58% (13 cases, CI 67.2-111.7) in the aseptic and septic group, respectively (p = 0.01).

CONCLUSIONS

EMA reconstruction after extensor mechanism disruptions in TKA is a reliable salvage procedure. The septic nature of the revision decreased the functionality of the knee joint after EMA, but it did not represent a risk factor for re-ruptures or recurrence of infection.

LEVEL OF EVIDENCE

Level III.

摘要

目的

全膝关节置换术(TKA)后伸肌机制损伤是一种灾难性并发症。同种异体伸肌机制重建术(EMA)已被描述为一种有效的挽救手术。其长期有效性以及在感染病例中的有效性仍在研究中。本文分析了EMA重建术用于无菌性和感染性翻修TKA后慢性伸肌机制失败的长期结果。

方法

从机构数据库中,回顾性确定了2005年至2015年期间35例行EMA重建术的翻修TKA患者。其中13例(37%)患者有假体周围关节感染(PJI)病史。平均随访时间为81.2个月(±34.7,范围3 - 120个月)。当伸肌滞后超过20°、膝关节协会评分(KSS)低于60分和/或进行同种异体移植翻修时,视为EMA失败。

结果

无菌组的平均KSS从35.9分(±16.9,范围0 - 54)提高到86.6分(±10.4,范围54 - 99)(p < 0.001),感染组从27.5分(±11.6,范围10 - 44)提高到79.4分(±16.3,范围48 - 94)(p < 0.001)。无菌组的伸肌滞后从48.4°(±14.5,范围30 - 90)变为4.6°(±10.8,范围0 - 50)(p < 0.001),感染组从56.5°(±20.8,范围30 - 90)变为6.1°(±6.8,范围0 - 20)(p < 0.001)。无菌组术后平均屈曲度为105.2°(±13.2,范围75 - 130),感染组为102.7°(±12.5,范围80 - 120)(p = 0.32)。无菌组发生3例失败(占病例的14%),感染组发生5例(占病例的38%)。无菌组和感染组10年的总体生存率分别为83.3%(22例,CI 94.2 - 121.7)和58%(13例,CI 67.2 - 111.7)(p = 0.01)。

结论

TKA伸肌机制破坏后进行EMA重建是一种可靠的挽救手术。翻修的感染性质降低了EMA术后膝关节的功能,但它不是再次断裂或感染复发的危险因素。

证据级别

三级。

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