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肝包虫囊肿合并肝细胞癌误诊:1 例报告。

Misdiagnosis of hepatic cystic echinococcosis complicated with hepatocellular carcinoma: A case report.

机构信息

Department of Graduate School, Qinghai University, Xining, Qinghai Province, China.

Department of General Surgery, Qinghai Provincial People's Hospital, Xining, Qinghai Province, China.

出版信息

Medicine (Baltimore). 2022 Dec 23;101(51):e32291. doi: 10.1097/MD.0000000000032291.

DOI:10.1097/MD.0000000000032291
PMID:36595756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9794291/
Abstract

RATIONALE

Hepatic cystic echinococcosis (CE) is a common zoonotic parasitic disease caused by the entry of Echinococcus granulosus eggs into human body. Surgical resection is the optimal treatment choice for hepatic CE. However, Coexistence of CE and hepatocellular carcinoma (HCC) have been reported with a rare incidence rate, which led to unsatisfactory prognosis after the operation.

PATIENT CONCERNS

A 69-year-old male patient was admitted to hospital because of "Upper abdominal pain and discomfort for more than 1 month and an aggravation for 10 days."

DIAGNOSIS

An elderly male herder who was initially diagnosed as hepatic CE, and none of the preoperative imaging test revealed the existence of HCC. Co-existence of hepatic CE and HCC was confirmed by the postoperative pathological examination.

INTERVENTIONS

The patient underwent "combined hepatic segmental resection, portal vein thrombectomy, portal vein repairment, hepatic hydatid internal capsule removal and external subtotal resection, cholecystectomy".

OUTCOMES

During follow-up after discharge, the patient did not regularly review and get further treatment and died 8 months after operation.

LESSONS

May improve the clinicians' understanding of CE complicated with HCC, and reduce the misdiagnosis of similar case, as well as provide guidance for clinical treatment.

摘要

背景

肝包虫病(CE)是一种常见的人畜共患寄生虫病,由细粒棘球绦虫虫卵进入人体引起。手术切除是肝 CE 的最佳治疗选择。然而,CE 合并肝细胞癌(HCC)的报道罕见,导致术后预后不佳。

病例介绍

一名 69 岁男性患者因“上腹疼痛不适 1 个月余,加重 10 天”入院。

诊断

该老年男性牧民最初被诊断为肝包虫病,术前影像学检查均未提示 HCC 的存在。术后病理检查证实了肝 CE 合并 HCC 的存在。

治疗

患者接受了“联合肝段切除术、门静脉血栓切除术、门静脉修补术、肝包虫内囊摘除术和外部分切除术、胆囊切除术”。

结果

出院后随访期间,患者未定期复查和进一步治疗,术后 8 个月死亡。

结论

可能提高临床医生对 CE 合并 HCC 的认识,减少类似病例的误诊,并为临床治疗提供指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d5c/9794291/0b62abe685e2/medi-101-e32291-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d5c/9794291/5b2c9c2b8011/medi-101-e32291-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d5c/9794291/c1b2119b83e4/medi-101-e32291-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d5c/9794291/e12ac2388469/medi-101-e32291-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d5c/9794291/0b62abe685e2/medi-101-e32291-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d5c/9794291/5b2c9c2b8011/medi-101-e32291-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d5c/9794291/c1b2119b83e4/medi-101-e32291-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d5c/9794291/e12ac2388469/medi-101-e32291-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d5c/9794291/0b62abe685e2/medi-101-e32291-g004.jpg

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