Zwijnenburg A, Alberts C, Jansen H M, Roos C M, Marcuse H R
The Netherlands Cancer Institute, Nuclear Medicine Department, Amsterdam.
Sarcoidosis. 1987 Sep;4(2):122-8.
In 14 patients with advanced stage pulmonary sarcoidosis the distribution of regional ventilation-perfusion ratios (V/Q) was obtained by quantitative analysis of ventilation-perfusion single photon emission computed tomography (SPECT) of the lungs. In 6 patients normal V/Q distributions were found with a decreased DLCO in only one of them. In 8 patients abnormal distributions of V/Q ratios were found. Six of these patients also had a decrease in diffusing capacity for CO (DLCO). It is suggested that the decrease in DLCO in these patients is partly a result of uneven distribution of V/Q ratios.
