针刺治疗帕尼单抗所致皮肤毒性：1例报告
Acupuncture in the Treatment of Panitumumab Skin Toxicity: A Case Report.
作者信息
Nahumi Tzach, Levy Ilana, Schiff Elad, Attias Samuel, Amromin Tatiana, Agbarya Abed
机构信息
Oncology Unit, Bnai Zion Medical Center, Haifa, Israel.
Complementary and Integrative Medicine Service, Bnai Zion Medical Center, Haifa, Israel.
出版信息
Complement Med Res. 2023;30(1):78-83. doi: 10.1159/000527853. Epub 2023 Jan 3.
BACKGROUND
Inflammatory skin rash resulting from treatment with epidermal growth factor receptor inhibitors may cause physical and mental disabling to patients treated for their oncologic condition and may, in some cases, lead to the cessation of biological treatment.
CASE REPORT
In this case report, acupuncture treatment was provided to a patient with metastatic colorectal carcinoma who developed skin toxicity from panitumumab including rash, itching, and skin inflammation. Itching, infection, and inflammation symptoms improved significantly following acupuncture, subsequently relapsed following treatment cessation, and improved once again following reintroduction of acupuncture.
CONCLUSION
Acupuncture may be effective in alleviating panitumumab-related skin inflammatory symptoms.
背景
表皮生长因子受体抑制剂治疗引起的炎性皮疹可能会给接受肿瘤治疗的患者带来身心障碍，在某些情况下还可能导致生物治疗中断。
病例报告
在本病例报告中，对一名转移性结直肠癌患者进行了针灸治疗，该患者因帕尼单抗出现皮肤毒性，包括皮疹、瘙痒和皮肤炎症。针灸治疗后，瘙痒、感染和炎症症状显著改善，治疗停止后症状复发，再次进行针灸治疗后症状再次改善。
结论
针灸可能有效缓解帕尼单抗相关的皮肤炎症症状。
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