García Diez Sara, De Nicolás Valdés Míriam, Diéguez Varela Cristina, Fernández Martínez Paula, Suárez Gil Patricio, Navarro Rodríguez Yolanda
Centro de Salud Contrueces, Principado de Asturias, Gijón, España.
Centro de Salud Contrueces, Principado de Asturias, Gijón, España.
Aten Primaria. 2023 Mar;55(3):102552. doi: 10.1016/j.aprim.2022.102552. Epub 2022 Dec 7.
To evaluate the effect of COVID-19 lockdown on the prescription of benzodiazepines by gender, age and district health departments.
Longitudinal observational study.
Primary care. Asturias (Spain) health district V.
People over 15 years of age with filled benzodiazepine prescriptions in between 2017 and 2020.
Benzodiazepine DHD (defined daily dose per 1000 habitants) mean difference between the period defined as pre-lockdown and lockdown. Additionally, the difference was adjusted for gender, sex and district health department and also with the interaction among them.
DHD mean pre-lockdown was 131.3 and 139.5 in the lockdown; this difference was significant in the global analysis (95% CI: 4.1-12.1). There was an increase in the DHD mean in the 60-74 age group (95% CI: 2.28-21.42), in the group over 90 years old (95% CI: 21.31-40.63) and in women (95% CI: 3.51-14.59). Finally, a decrease in the DHD mean of V11 (95% CI: -29 to -0.66) and V14 (95% CI: -54.28 to -25.04) district health departments was observed.
Certain subgroups show a change in the pattern of benzodiazepine prescription without being able to relate this to the lockdown. We believe that there could be some inertia in the prescription of psychiatric medication according to the biopsychosocial characteristics of the patients; it is important to detect this in order to avoid the medicalization of psychological disorders.
按性别、年龄和地区卫生部门评估新冠疫情封锁措施对苯二氮䓬类药物处方的影响。
纵向观察性研究。
初级保健机构。西班牙阿斯图里亚斯卫生区V。
2017年至2020年间有苯二氮䓬类药物处方记录的15岁以上人群。
将疫情封锁前时期与封锁时期进行比较，计算苯二氮䓬类药物的限定日剂量（每1000居民的每日规定剂量，DHD）的平均差异。此外，该差异还根据性别、年龄和地区卫生部门进行了调整，并考虑了它们之间的相互作用。
封锁前DHD平均值为131.3，封锁期间为139.5；在总体分析中，这一差异具有统计学意义（95%置信区间：4.1 - 12.1）。60 - 74岁年龄组（95%置信区间：2.28 - 21.42）、90岁以上年龄组（95%置信区间：21.31 - 40.63）以及女性（95%置信区间：3.51 - 14.59）的DHD平均值有所增加。最后，观察到V11（95%置信区间：-29至-0.66）和V14（95%置信区间：-54.28至-25.04）地区卫生部门的DHD平均值有所下降。
某些亚组的苯二氮䓬类药物处方模式发生了变化，但无法将其与封锁措施联系起来。我们认为，根据患者的生物心理社会特征，精神科药物处方可能存在一定的惯性；重要的是要发现这一点，以避免心理障碍的医学化。
