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Effects of dietary copper and molybdenum on copper status, cytokine production, and humoral immune response of calves.日粮铜和钼对犊牛铜状态、细胞因子产生及体液免疫反应的影响。
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本文引用的文献

1
Influence of Molybdenum in Drinking Water or Feed on Copper Metabolism in Cattle-A Review.饮用水或饲料中的钼对牛铜代谢的影响——综述
Animals (Basel). 2021 Jul 13;11(7):2083. doi: 10.3390/ani11072083.
2
Molybdenum Exposure in Drinking Water Vs Feed Impacts Apparent Absorption of Copper Differently in Beef Cattle Consuming a High-Forage Diet.饮水中钼暴露与饲料对高粗饲料饮食下肉牛铜表观吸收率的影响不同。
Biol Trace Elem Res. 2021 Aug;199(8):2913-2918. doi: 10.1007/s12011-020-02440-0. Epub 2020 Oct 23.
3
The effects of molybdenum water concentration on feedlot performance, tissue mineral concentrations, and carcass quality of feedlot steers,钼水浓度对育肥牛生长性能、组织矿物质浓度及胴体品质的影响
J Anim Sci. 2017 Jun;95(6):2758-2766. doi: 10.2527/jas.2016.1333.
4
Some preliminary observations on the effect of molybdenum on copper metabolism in herbivorous animals.关于钼对草食动物铜代谢影响的一些初步观察
Aust Vet J. 1945;21(3):70-2. doi: 10.1111/j.1751-0813.1945.tb04462.x.
5
Management of water quality for beef cattle.肉牛的水质管理
Vet Clin North Am Food Anim Pract. 2007 Mar;23(1):91-103. doi: 10.1016/j.cvfa.2006.12.002.
6
Modest copper supplementation blocks molybdenosis in cattle.适量补充铜可预防牛的钼中毒。
J Vet Diagn Invest. 2006 Nov;18(6):566-72. doi: 10.1177/104063870601800607.
7
A rapid colorimetric method for the quantitative determination of copper oxidase activity (ceruloplasmin).一种用于定量测定铜氧化酶活性(血浆铜蓝蛋白)的快速比色法。
Clin Chem. 1958 Dec;4(6):519-23.
8
Effects of dietary copper concentration and source on performance and copper status of growing and finishing steers.日粮铜浓度和来源对生长育肥牛生产性能及铜状况的影响。
J Anim Sci. 2000 Sep;78(9):2446-51. doi: 10.2527/2000.7892446x.
9
The effects of low-copper diets with or without supplemental molybdenum on specific immune responses of stressed cattle.低铜日粮添加或不添加钼对应激牛特异性免疫反应的影响。
J Anim Sci. 1999 Jan;77(1):230-7. doi: 10.2527/1999.771230x.
10
Effects of dietary copper and molybdenum on copper status, cytokine production, and humoral immune response of calves.日粮铜和钼对犊牛铜状态、细胞因子产生及体液免疫反应的影响。
J Dairy Sci. 1998 Dec;81(12):3286-92. doi: 10.3168/jds.S0022-0302(98)75893-X.

饮水中长期钼暴露对采食高粗饲料肉牛钼代谢和生产性能的影响。

The Effects of Long-term Molybdenum Exposure in Drinking Water on Molybdenum Metabolism and Production Performance of Beef Cattle Consuming a High Forage Diet.

机构信息

Department of Animal Science, Colorado State University, Fort Collins, CO, USA.

Department of Animal Science, Faculdade de Ciências Agrárias E Jaboticabal, Jaboticabal, Sao Paulo, Brasil.

出版信息

Biol Trace Elem Res. 2023 Sep;201(9):4360-4373. doi: 10.1007/s12011-022-03532-9. Epub 2023 Jan 5.

DOI:10.1007/s12011-022-03532-9
PMID:36600169
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10350436/
Abstract

Fifty-four multiparous beef cows with calves were used to evaluate the effects of Mo source (feed or water) on reproduction, mineral status, and performance over two cow-calf production cycles (553 days). Cows were stratified by age, body weight, liver Cu, and Mo status and were then randomly assigned to one of six treatment groups. Treatments were (1) negative control (NC; basal diet with no supplemental Mo or Cu), (2) positive control (NC + Cu; 3 mg of supplemental Cu/kg DM), (3) NC + 500 µg Mo/L from Na2MoO4·2H2O supplied in drinking water, (4) NC + 1000 µg Mo/L of Na2MoO4·2H2O supplied in drinking water, (5) NC + Mo 1000-water + 3 mg of supplemental Cu/kg DM, and (6) NC + 3.0 mg of supplemental Mo/kg diet DM from Na2MoO4·2H2O. Animals were allowed ad libitum access to both harvested grass hay (DM basis: 6.6% crude protein; 0.15% S, 6.7 mg Cu/kg, 2.4 mg Mo/kg) and water throughout the experiment. Calves were weaned at approximately 6 months of age each year. Dietary Cu concentration below 10.0 mg Cu/kg DM total diet reduced liver and plasma Cu concentrations to values indicative of a marginal Cu deficiency in beef cows. However, no production parameters measured in this experiment were affected by treatment. Results suggest that Mo supplemented in water or feed at the concentrations used in this experiment had minimal impact on Cu status and overall performance.

摘要

54 头经产奶牛及其犊牛用于评估两种奶牛-犊牛生产周期(553 天)中钼源(饲料或水)对繁殖、矿物质状况和性能的影响。奶牛按年龄、体重、肝脏铜和钼状况进行分层,然后随机分配到六个处理组之一。处理组为:(1)阴性对照(NC;基础日粮,不补充铜或钼),(2)阳性对照(NC+Cu;补充 3mg/kg 干物质的铜),(3)饮水提供 Na2MoO4·2H2O 中的 500µg Mo/L,(4)饮水提供 Na2MoO4·2H2O 中的 1000µg Mo/L,(5)饮水提供 Na2MoO4·2H2O 中的 1000µg Mo/L 和 3mg/kg 干物质的补充铜,(6)饲料中提供 3.0mg/kg 干物质的钼(来自 Na2MoO4·2H2O)。动物可自由采食收获的干草(干物质基础:6.6%粗蛋白;0.15%硫,6.7mg Cu/kg,2.4mg Mo/kg)和水。犊牛每年大约在 6 个月时断奶。日粮铜浓度低于 10.0mg/kg 干物质总日粮会降低肝脏和血浆铜浓度,表明肉牛处于铜缺乏的边缘状态。然而,本实验中测量的生产参数不受处理影响。结果表明,以本实验中使用的浓度在水中或饲料中补充钼对铜状态和整体性能的影响很小。