作为前瞻性对照临床治疗试验评估工具的综合质量评分（CQS）：基本原理与现有证据
The Composite Quality Score (CQS) as an Appraisal Tool for Prospective, Controlled Clinical Therapy Trials: Rationale and Current Evidence.
作者信息
Mickenautsch Steffen, Rupf Stefan, Miletić Ivana, Yengopal Veerasamy
机构信息
Faculty of Dentistry, University of the Western Cape, Francie van Zijl Avenue, Tygerberg/Cape Town, 7505, South Africa.
Department of Community Dentistry, School of Oral Health Sciences, Faculty of Health Sciences, University of the Witwatersrand, 7 York Rd., Parktown/Johannesburg 2193, South Africa.
出版信息
Rev Recent Clin Trials. 2023;18(1):28-33. doi: 10.2174/1574887118666230104152245.
BACKGROUND
Current evidence appraisal concepts, such as the Assessment, Development and Evaluation (GRADE) approach and Cochrane's Risk of Bias (RoB) tool, rely on assumptions related to the classic problem of inductive reasoning and may suffer from insufficient inter-rater reliability.
DISCUSSION
The Composite Quality Score (CQS) has emerged as a possible trial appraisal tool that does not rely on inductive assumptions and has been shown to be of potentially very high inter-rater reliability.
CONCLUSION
Although the current CQS concept is still under development, its current evidence is encouraging and justifies further study. This article presents the rationale and currently available research concerning the CQS and shows where further research is required.
背景
当前的证据评估概念，如评估、发展与评价（GRADE）方法以及Cochrane偏倚风险（RoB）工具，依赖于与归纳推理经典问题相关的假设，并且可能存在评分者间信度不足的问题。
讨论
综合质量评分（CQS）已成为一种可能的试验评估工具，它不依赖归纳假设，并且已被证明具有潜在的非常高的评分者间信度。
结论
尽管当前的CQS概念仍在发展中，但其现有证据令人鼓舞，值得进一步研究。本文介绍了CQS的基本原理和目前可用的研究，并指出了需要进一步研究的方向。
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