用于测量左心室心肌致密化不全中肌小梁的三维全心脏心脏磁共振成像序列
Three-dimensional Whole-Heart Cardiac MRI Sequence for Measuring Trabeculation in Left Ventricular Noncompaction.
作者信息
Polacin Malgorzata, Károlyi Mihály, Wilzeck Verena, Eberhard Matthias, Gotschy Alexander, Alkadhi Hatem, Kozerke Sebastian, Manka Robert
机构信息
Institute of Diagnostic and Interventional Radiology (M.P., M.K., M.E., H.A., R.M.) and Department of Cardiology, University Heart Center (V.W., A.G., R.M.), University Hospital Zurich, University of Zurich, Raemistrasse 100, 8091 Zurich, Switzerland; and Institute for Biomedical Engineering, University and ETH Zurich, Gloriastrasse 35, 8092 Zurich, Switzerland (M.P., A.G., S.K., R.M.).
出版信息
Radiol Cardiothorac Imaging. 2022 Nov 17;4(6):e220109. doi: 10.1148/ryct.220109. eCollection 2022 Dec.
PURPOSE
To compare three-dimensional (3D) whole-heart MRI with isotropic submillimeter resolution with standard two-dimensional (2D) cine MRI in measuring the bilayered myocardium in left ventricular noncompaction (LVNC).
MATERIALS AND METHODS
Twenty-four patients with LVNC (mean age, 42 years ± 16 [SD]) were retrospectively enrolled between October 2011 and July 2020. Compacted myocardium (CM) and noncompacted myocardium (NCM) were measured in long axis (Petersen approach) and short axis (Jacquier approach) at 3D whole-heart and 2D cine MRI by two independent readers. Image quality (1 = excellent, 2 = adequate, 3 = nondiagnostic), considering discrimination between NCM and CM and CM and adjacent tissue, was evaluated. Pearson, Spearman, and intraclass correlation tests were used as statistical tests.
RESULTS
In long-axis measurements, the correlation between both sequences was moderate to strong for CM (Pearson, 0.66-0.79; Spearman, 0.61-0.68) and strong to very strong for NCM (Pearson, 0.90-0.97; Spearman, 0.77-0.91). Intraclass correlation coefficient (ICC) in 3D whole-heart MRI was 0.90 (95% CI: 0.78, 0.95) for CM and 0.94 (95% CI: 0.84, 0.97) for NCM, while ICC in 2D cine MRI was 0.77 (95% CI: 0.55, 0.89) for CM and 0.87 (95% CI: 0.72, 0.94) for NCM. Short-axis CM and NCM measurements had a strong to very strong correlation between both sequences (Pearson, 0.86-0.98; Spearman, 0.82-0.98). ICC in 3D whole-heart MRI was 0.96 (95% CI: 0.94, 0.99) for CM and 0.98 (95% CI: 0.97, 0.99) for NCM, while ICC in 2D cine MRI was 0.82 (95% CI: 0.63, 0.92) for CM and 0.87 (95% CI: 0.72, 0.94) for NCM. 3D whole-heart MRI demonstrated higher image quality than did 2D cine MRI ( < .001).
CONCLUSION
3D whole-heart MRI revealed higher image quality, with better structure discrimination and interobserver agreement in LVNC measurements, compared with standard 2D cine images. MR Imaging, Cardiac, Cardiovascular Magnetic Resonance, Left Ventricular Noncompaction, Free-breathing Imaging Technique © RSNA, 2022See also the commentary by Jensen and Petersen in this issue.
目的
比较具有各向同性亚毫米分辨率的三维（3D）全心MRI与标准二维（2D）电影MRI在测量左心室心肌致密化不全（LVNC）中的双层心肌方面的差异。
材料与方法
回顾性纳入2011年10月至2020年7月期间的24例LVNC患者（平均年龄42岁±16[标准差]）。由两名独立阅片者在3D全心和2D电影MRI上，于长轴（彼得森方法）和短轴（雅克奎方法）测量致密心肌（CM）和非致密心肌（NCM）。评估图像质量（1=优秀，2=尚可，3=无法诊断），考虑NCM与CM以及CM与相邻组织之间的区分情况。采用Pearson、Spearman和组内相关检验作为统计检验。
结果
在长轴测量中，两种序列之间对于CM的相关性为中度至强（Pearson，0.66 - 0.79；Spearman，0.61 - 0.68），对于NCM的相关性为强至非常强（Pearson，0.90 - 0.97；Spearman，0.77 - 0.91）。3D全心MRI中CM的组内相关系数（ICC）为0.90（95%CI：0.78，0.95），NCM为0.94（95%CI：0.84，0.97），而2D电影MRI中CM的ICC为0.77（95%CI：0.55，0.89），NCM为0.87（95%CI：0.72，0.94）。短轴CM和NCM测量中，两种序列之间具有强至非常强的相关性（Pearson，0.86 - 0.98；Spearman，0.82 - 0.98）。3D全心MRI中CM的ICC为0.96（95%CI：0.94，0.99），NCM为0.98（95%CI：0.97，0.99），而2D电影MRI中CM的ICC为0.82（95%CI：0.63，0.92），NCM为0.87（95%CI：0.72，0.94）。3D全心MRI显示出比2D电影MRI更高的图像质量（P<0.001）。
结论
与标准2D电影图像相比，3D全心MRI在LVNC测量中显示出更高的图像质量，具有更好的结构区分度和观察者间一致性。磁共振成像、心脏、心血管磁共振、左心室心肌致密化不全、自由呼吸成像技术 ©RSNA，2022另见本期詹森和彼得森的评论。
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