Lauricella Sara, Peyser Daniel, Carrano Francesco Maria, Sylla Patricia
Division of Colon and Rectal Surgery, Department of Surgery, Icahn School of Medicine at Mount Sinai Hospital, 5 East 98Th Street, Box 1259, New York, NY, 10029, USA.
Department of General Surgery, Busto Arsizio Circolo Hospital ASST-Valle Olona, Busto Arsizio, Italy.
J Gastrointest Surg. 2023 Mar;27(3):615-625. doi: 10.1007/s11605-022-05564-x. Epub 2023 Jan 5.
Indocyanine green fluorescence angiography (ICG-FA) has been used in colorectal surgery to assess anastomotic perfusion and reduce the risks of anastomotic leaks. The main objective of this paper is to review the data on the transanal application of ICG-FA for the intraluminal assessment of colorectal anastomosis.
A literature search was conducted for articles published between 2011 and 2021 using PubMed and Cochrane databases, related to the application of ICG for the intraluminal assessment of colorectal anastomosis. Original scientific manuscripts, review articles, meta-analyses, and case reports were considered eligible.
A total of 305 studies have been identified. After abstract screening for duplicates, 285 articles remained. Of those, 271 were not related to the topic of interest, 4 were written in a language other than English, and 4 had incomplete data. Six articles remained for the final analysis. The intraluminal assessment of colorectal anastomosis with ICG-FA is feasible, safe, and may reduce the incidence of leaks.
The intraluminal assessment of anastomotic perfusion via ICG-FA may be a promising novel application of ICG technology. More data is needed to support this application further to reduce leak rates after colorectal surgery, and future randomized clinical trials are awaited.
吲哚菁绿荧光血管造影术（ICG-FA）已用于结直肠手术，以评估吻合口灌注情况并降低吻合口漏的风险。本文的主要目的是回顾关于经肛门应用ICG-FA进行结直肠吻合口腔内评估的数据。
使用PubMed和Cochrane数据库对2011年至2021年发表的与ICG用于结直肠吻合口腔内评估相关的文章进行文献检索。原始科学手稿、综述文章、荟萃分析和病例报告均被视为符合条件。
共识别出305项研究。在对重复项进行摘要筛选后，剩余285篇文章。其中，271篇与感兴趣的主题无关，4篇用非英语撰写，4篇数据不完整。最终分析保留6篇文章。用ICG-FA进行结直肠吻合口腔内评估是可行、安全的，且可能降低漏出发生率。
通过ICG-FA进行吻合口灌注的腔内评估可能是ICG技术一项有前景的新应用。需要更多数据来进一步支持该应用，以降低结直肠手术后的漏出率，期待未来进行随机临床试验。
