类固醇及相关产品。LIV。11-氧杂类固醇的合成。VI。11-氧杂睾酮的合成。
Steroids and related products. LIV. The synthesis of 11-oxa steroids. VI. The synthesis of 11-oxatestosterone.
作者信息
Salvi V S, Mukherjee D, Engel C R
机构信息
Department of Chemistry, Université Laval, Quebec, Canada.
出版信息
Steroids. 1986 Jul-Aug;48(1-2):47-53. doi: 10.1016/0039-128x(86)90040-1.
PMID:3660439
Abstract
The synthesis of 11-oxatestosterone from 11-oxa-5 alpha-androstane-3,17-dione, which is available from hecogenin, is described. The product shows, in comparison with the natural hormone, diminished androgenic and anabolic activities.
摘要
描述了从可由海柯皂苷元制得的11-氧杂-5α-雄甾烷-3,17-二酮合成11-氧杂睾酮的方法。与天然激素相比，该产物的雄激素活性和合成代谢活性有所降低。
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