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高血压血管功能的当前研究课题。

Current topic of vascular function in hypertension.

机构信息

Department of Regenerative Medicine, Division of Radiation Medical Science, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.

Division of Regeneration and Medicine, Medical Center for Translational and Clinical Research, Hiroshima University Hospital, Hiroshima, Japan.

出版信息

Hypertens Res. 2023 Mar;46(3):630-637. doi: 10.1038/s41440-022-01147-0. Epub 2023 Jan 5.

DOI:10.1038/s41440-022-01147-0
PMID:36604472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9813887/
Abstract

Vascular function assessment is useful for the evaluation of atherosclerosis severity, which may provide additional information for cardiovascular risk stratification. In addition, vascular function assessment is helpful for a better understanding of pathophysiological associations between vascular dysfunction and cardiometabolic disorders. In 2020 and 2021, although coronavirus disease 2019 (COVID-19) was still a worldwide challenge for health care systems, many excellent articles regarding vascular function were published in Hypertension Research and other major cardiovascular and hypertension journals. In this review, we summarize new findings on vascular function and discuss the association between vascular function and COVID-19, the importance of lifestyle modifications for the maintenance of vascular function, and the usefulness of vascular function tests for cardiovascular risk assessment. We hope this review will be helpful for the management of cardiovascular risk factors, including hypertension and cardiovascular diseases, in clinical practice.

摘要

血管功能评估对于评估动脉粥样硬化的严重程度是有用的,这可能为心血管风险分层提供额外的信息。此外,血管功能评估有助于更好地理解血管功能障碍与心血管代谢疾病之间的病理生理关联。尽管 2020 年和 2021 年,2019 冠状病毒病(COVID-19)仍然是全球医疗系统面临的挑战,但许多关于血管功能的优秀文章发表在《高血压研究》和其他主要的心血管和高血压期刊上。在这篇综述中,我们总结了血管功能的新发现,并讨论了血管功能与 COVID-19 的关系、生活方式改变对维持血管功能的重要性,以及血管功能测试在心血管风险评估中的有用性。我们希望这篇综述将有助于管理包括高血压和心血管疾病在内的心血管危险因素,在临床实践中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b116/9813887/9658f8cdea0e/41440_2022_1147_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b116/9813887/36803ef664b1/41440_2022_1147_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b116/9813887/9658f8cdea0e/41440_2022_1147_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b116/9813887/36803ef664b1/41440_2022_1147_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b116/9813887/9658f8cdea0e/41440_2022_1147_Fig2_HTML.jpg

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Hypertens Res. 2023 Sep;46(9):2145-2158. doi: 10.1038/s41440-023-01354-3. Epub 2023 Jun 27.