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《剖宫产术后胎脂性腹膜炎致急性腹痛的病例系列研究》

Vernix Caseosa Peritonitis Causing Acute Abdomen After Cesarean Section: A Case Series.

机构信息

Department of Medicine, Bankstown-Lidcombe Hospital, Bankstown, NSW, Australia.

Women and Babies Research, Kolling Institute, The University of Sydney, St Leonards, NSW, Australia.

出版信息

Am J Case Rep. 2023 Jan 6;24:e938276. doi: 10.12659/AJCR.938276.

Abstract

BACKGROUND Vernix caseosa peritonitis (VCP) is a rare complication that typically presents following an otherwise uneventful cesarean section. Leakage of vernix caseosa into the peritoneum is thought to elicit a granulomatous foreign body reaction. Symptoms can be similar to other acute abdominal conditions, and diagnosis is confirmed by intraoperative findings and histological examination. Peritoneal lavage with supportive measures is the mainstay of treatment and recovery. CASE REPORT Case 1 was a 30-year-old woman who developed right iliac fossa pain, fever, tachycardia, and tachypnea less than a week after her lower segment cesarean section (LSCS). She underwent a laparoscopy for a peritonitic abdomen and concern for intra-abdominal sepsis. A peritoneal biopsy demonstrated histological changes consistent with VCP. Case 2 was a 39-year-old woman who underwent a LSCS. After discharge, she re-presented with generalized abdominal pain. With computed tomography (CT) scan findings suggestive of appendicitis, an appendectomy was performed, and vernix caseosa was detected in all quadrants. Case 3 was a 33-year-old woman who presented with fever, vomiting, diarrhea, and iliac fossa pain 9 days following an LSCS. She was given analgesia and antibiotics for a pelvic fluid collection noted on CT scan. She re-presented with tense swelling and pain above her cesarean section incision. Laparoscopy revealed adhesions over the lower abdomen and pelvis and white plaques suggestive of vernix caseosa along the peritoneal side walls. CONCLUSIONS The rising incidence of cesarean births worldwide creates the potential for increased numbers of VCP cases. Greater recognition of VCP is warranted to prevent unnecessary procedures.

摘要

背景

胎皮脂腹膜炎(VCP)是一种罕见的并发症,通常在剖宫产术过程顺利后出现。胎皮脂进入腹膜被认为会引起肉芽肿性异物反应。症状可能与其他急性腹部情况相似,诊断通过术中发现和组织学检查来确认。腹膜灌洗和支持措施是主要的治疗方法,恢复良好。

病例报告

病例 1 为 30 岁女性,剖宫产后不到一周出现右髂窝疼痛、发热、心动过速和呼吸急促。她因腹膜炎性腹部和腹腔内脓毒症的担忧而行腹腔镜检查。腹膜活检显示符合 VCP 的组织学改变。病例 2 为 39 岁女性,行剖宫产后出院,再次出现全腹疼痛。CT 扫描结果提示阑尾炎,行阑尾切除术,在所有象限均发现胎皮脂。病例 3 为 33 岁女性,剖宫产后 9 天出现发热、呕吐、腹泻和髂窝疼痛。她因 CT 扫描发现盆腔积液而接受了镇痛和抗生素治疗。她再次出现紧张肿胀和剖宫产切口上方疼痛。腹腔镜检查显示下腹部和骨盆粘连,腹膜侧壁有白色斑块提示胎皮脂。

结论

全球剖宫产率的上升可能导致 VCP 病例增加。提高对 VCP 的认识,以避免不必要的手术是有必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2bd/9830522/f8dc0de7e3bc/amjcaserep-24-e938276-g001.jpg

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