Tawfik O, Prather J, Bhatia P, Woodroof J, Gunter J, Webb P
Department of Pathology and Laboratory Medicine, Kansas University Medical Center, Kansas City 66160, USA.
J Reprod Med. 1998 Jun;43(6):547-50.
Vernix caseosa peritonitis is a rare complication of cesarean section with distinctive histopathologic findings.
Vernix caseosa peritonitis occurred in a 28-year-old, pregnant woman following emergency cesarean section. Exploratory laparotomy revealed right subphrenic and perihepatic fluid collections with multiple small abdominal abscesses. Cytopathologic examination of the peritoneal lavage specimen showed a purulent inflammatory exudate admixed with occasional squamous debris, portions of hair shafts, meconium pigment, and foamy and multinucleated giant cells. During hospitalization the patient had developed Clostridium perfringens acute endometritis, presumably due to aggressive treatment with broad-spectrum antibiotics.
Pathologists are in a unique position to make the correct diagnosis in an otherwise-ambiguous clinical presentation because of the distinctive histopathologic and cytopathologic findings of this entity. Computed tomography-guided fine needle aspiration cytologic evaluation can be diagnostic in such cases.
胎脂性腹膜炎是剖宫产术后一种罕见的并发症,具有独特的组织病理学表现。
一名28岁孕妇在急诊剖宫产术后发生胎脂性腹膜炎。剖腹探查发现右膈下和肝周有积液,并有多个小腹部脓肿。腹腔灌洗标本的细胞病理学检查显示为脓性炎性渗出物,混有偶尔的鳞状碎屑、部分毛干、胎粪色素以及泡沫状和多核巨细胞。住院期间,患者发生了产气荚膜梭菌急性子宫内膜炎,可能是由于使用广谱抗生素进行积极治疗所致。
由于该实体独特的组织病理学和细胞病理学表现,病理学家在临床表现不明确的情况下处于做出正确诊断的独特地位。计算机断层扫描引导下的细针穿刺细胞学评估在这类病例中可具有诊断价值。