Wu Xiao-Chun, Jia Xiao-Bin, Ma Wei-Kun, Wu Qi, Wang Long, Yang Bing, Feng Liang
School of Traditional Chinese Pharmacy, China Pharmaceutical University Nanjing 211198, China.
School of Traditional Chinese Pharmacy, China Pharmaceutical University Nanjing 211198, China Jiangsu Pharmaceutical Museum, China Pharmaceutical University Nanjing 211198, China.
Zhongguo Zhong Yao Za Zhi. 2022 Dec;47(23):6278-6286. doi: 10.19540/j.cnki.cjcmm.20220722.102.
Rare and endangered animal medicine, a kind of important Chinese medicine, plays an irreplaceable role in the prevention and treatment of serious acute and chronic diseases and major diseases. Due to resource limitation and depletion and the increasing demand, rare and endangered medicinal animal resources have been drastically reduced or even extinct, which threatens the inheritance of traditional Chinese medicine, the integrity of clinical medicine, and the development of the traditional Chinese medicine industry. For the protection and sustainable utilization of Chinese medicinal resources, artificial substitutes came into being. However, there is still a lack of systematic research on the pharmacological effects and clinical applications of artificial substitutes and whether they can completely replace the original medicinal materials in clinical practice. Therefore, this study focuses on the status quo of rare and endangered animal medicinal materials and their artificial substitutes that have been marketed. To be specific, the two were compared and whether the artificial substitutes can completely replace the original medicinal materials was analyzed. In addition, constructive suggestions on the industrialization of artificial substitutes were put forward, which was expected to promote the sustainable development of Chinese medicinal resources.
珍稀濒危动物药作为一种重要的中药，在防治急慢性重症和重大疾病方面发挥着不可替代的作用。由于资源的限制与枯竭以及需求的不断增加，珍稀濒危药用动物资源已大幅减少甚至灭绝，这威胁到了中医药的传承、临床医学的完整性以及中药产业的发展。为了保护和可持续利用中药资源，人工替代品应运而生。然而，对于人工替代品的药理作用、临床应用以及它们在临床实践中能否完全替代原药材，仍缺乏系统的研究。因此，本研究聚焦于已上市的珍稀濒危动物药材及其人工替代品的现状。具体而言，对两者进行了比较，并分析了人工替代品能否完全替代原药材。此外，还针对人工替代品的产业化提出了建设性建议，期望能促进中药资源的可持续发展。
