Zhang Cheng-Cai, Wang Sheng, Wang Yue-Feng, Wang Hong-Yang, Qin Ming, Dai Xiao-Yu, Yan Bin-Bin, Guo Xiu-Zhi, Zhou Li, Lin Huai-Bin, Guo Lan-Ping
State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences Beijing 100700, China.
State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences Beijing 100700, China Dexing Research and Training Center of Chinese Medical Sciences Dexing 334213, China.
Zhongguo Zhong Yao Za Zhi. 2023 Mar;48(5):1186-1193. doi: 10.19540/j.cnki.cjcmm.20221017.104.
Chinese medicinal resources are the cornerstone of the sustainable development of traditional Chinese medicine industry. However, due to the fecundity of species, over-exploitation, and limitations of artificial cultivation, some medicinal plants are depleted and even endangered. Tissue culture, a breakthrough technology in the breeding of traditional Chinese medicinal materials, is not limited by time and space, and can allow the production on an annual basis, which plays an important role in the protection of Chinese medicinal resources. The present study reviewed the applications of tissue culture of medicinal plants in the field of Chinese medicinal resources, including rapid propagation of medicinal plant seedlings, breeding of novel high-yield and high-quality cultivars, construction of a genetic transformation system, and production of secondary metabolites. Meanwhile, the current challenges and suggestions for the future development of this field were also proposed.
中药资源是中医药产业可持续发展的基石。然而，由于物种繁殖力、过度开发以及人工栽培的局限性，一些药用植物资源枯竭甚至濒危。组织培养作为中药材育种中的一项突破性技术，不受时间和空间限制，可实现周年生产，在保护中药资源方面发挥着重要作用。本研究综述了药用植物组织培养在中药资源领域的应用，包括药用植物种苗的快速繁殖、新型高产优质品种的培育、遗传转化体系的构建以及次生代谢产物的生产。同时，还提出了该领域当前面临的挑战以及对未来发展的建议。
