Peng Xiao-Yun, Ren Yi-Feng, Dong Jing, Fu Xi, You Feng-Ming
Traditional Chinese Medicine Regulating Metabolic Diseases Key Laboratory of Sichuan Province,Hospital of Chengdu University of Traditional Chinese Medicine Chengdu 610075, China.
Traditional Chinese Medicine Regulating Metabolic Diseases Key Laboratory of Sichuan Province,Hospital of Chengdu University of Traditional Chinese Medicine Chengdu 610075, China Tumor Research Institute, Chengdu University of Traditional Chinese Medicine Chengdu 610075, China.
Zhongguo Zhong Yao Za Zhi. 2022 Dec;47(23):6505-6513. doi: 10.19540/j.cnki.cjcmm.20220829.501.
This study aims to analyze the current status and development trend of the prevention and treatment of pulmonary nodules(PN) with traditional Chinese medicine(TCM) based on knowledge map and to provide both references and suggestions for future research directions. CNKI, Wanfang, VIP, and SinoMed were searched for relevant papers from the inception to December 31, 2021. Eligible articles were included according to the inclusion and exclusion criteria. The line chart was drawn based on the annual publication volume of articles, and the research interests of this field were learned. The knowledge maps of prevention and treatment of PN with TCM were drawn in CiteSpace 5.8.R1, and the authors, institutions, contents, and hotspots were analyzed. A total of 122 articles were included and the line chart demonstrated that the annual publication volume has been rising since 2018. According to the knowledge maps, the most prolific author was ZHANG Xiao-mei and there were four main research teams. Beijing University of Chinese Medicine and its affiliated hospitals were in a leading position in this field. The main research contents were disease, pathogenesis, and treatment, and the hotspots were data mining and TCM syndrome. The research on prevention and treatment of PN with TCM has become an increasing field of interest in recent years. In the future, the cross-regional cooperation and communication between research teams and institutions should be strengthened for more real-world studies and basic studies about the prevention and treatment of PN with TCM, so that the high-level evidence can be obtained and the underlying mechanisms of TCM formulae in the treatment of PN be clarified.
本研究旨在基于知识图谱分析中医药防治肺结节的现状与发展趋势，为未来研究方向提供参考与建议。检索中国知网、万方、维普和中国生物医学文献数据库中从建库至2021年12月31日的相关论文。根据纳入与排除标准纳入合格文章。基于文章年发表量绘制折线图，了解该领域的研究热点。在CiteSpace 5.8.R1中绘制中医药防治肺结节的知识图谱，分析作者、机构、内容和热点。共纳入122篇文章，折线图显示自2018年以来年发表量一直在上升。根据知识图谱，发文量最多的作者是张小梅，有四个主要研究团队。北京中医药大学及其附属医院在该领域处于领先地位。主要研究内容为疾病、发病机制和治疗，热点为数据挖掘和中医证候。近年来，中医药防治肺结节的研究越来越受到关注。未来，应加强研究团队和机构之间的跨区域合作与交流，开展更多关于中医药防治肺结节的真实世界研究和基础研究，以获得高级别证据，阐明中药方剂治疗肺结节的潜在机制。
