Alrijne Wound Centre, Alrijne Ziekenhuis, Leiderdorp, The Netherlands.
Department of Surgery, Alrijne Ziekenhuis, Leiderdorp, The Netherlands.
Int Wound J. 2023 Aug;20(6):1866-1873. doi: 10.1111/iwj.14045. Epub 2023 Jan 5.
The diabetic foot ulcer (DFU) and Charcot Neuroarthropathy (CN) are serious complications of diabetes mellitus in which wound closure is complex to achieve. Treating recurrent DFU in patients with a combination of infection, ischemia, and deformities is extremely challenging and this group of patients has a very poor outcome. This case series describes the outcomes of patients with a recurrent DFU and CN, with a mean SINBAD score of 4 and of which 40% had a TCS of D3, using a multidisciplinary protocol that includes reconstructive foot and ankle surgery. In 24/35 (69%) of patients, wound closure was achieved after a mean of 75 days postoperatively. The mean ulcer-free period was 358 days. The mean number of interventions was 6.7 (range 3-9). Post treatment 27/35 (77%) of patients was mobile, without additional amputation or ulcer recurrence. This study shows that wound closure and a long ulcer-free period can be achieved in patients with a DFU and CN and its multifactorial underlying diseases when treated in a multidisciplinary team, including reconstructive foot and ankle surgery.
糖尿病足溃疡(DFU)和夏科氏关节病(CN)是糖尿病的严重并发症,伤口愈合复杂。治疗感染、缺血和畸形并存的复发性 DFU 极具挑战性,此类患者的预后非常差。本病例系列描述了一组 SINBAD 平均评分为 4 分且有 40%的患者 TCS 分级为 D3 的复发性 DFU 和 CN 患者的治疗结果,这些患者采用了包括足部和踝关节重建手术在内的多学科治疗方案。在 35 例患者中有 24 例(69%)在术后平均 75 天实现了伤口闭合。无溃疡期的平均时间为 358 天。平均干预次数为 6.7 次(范围 3-9 次)。治疗后,35 例患者中有 27 例(77%)可活动,无进一步截肢或溃疡复发。本研究表明,在多学科团队治疗下,包括足部和踝关节重建手术在内,患有 DFU 和 CN 及其多种潜在疾病的患者可以实现伤口闭合和较长的无溃疡期。