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注射溶脂术后非结核分枝杆菌引起的皮肤和软组织感染

Skin and soft tissue infection of Nontuberculous mycobacterium after injection lipolysis.

作者信息

Yang Yi, Li Shiyi, Zhang Lixia, Fu Huijuan, Zhou Guiwen, Chen Minliang

机构信息

Senior Department of Burns and Plastic Surgery, the Fourth Medical Center of PLA General Hospital, Beijing, China.

Chinese PLA Medical School, Beijing, China.

出版信息

J Cosmet Dermatol. 2023 Apr;22(4):1207-1212. doi: 10.1111/jocd.15591. Epub 2023 Jan 6.

Abstract

BACKGROUND

Injection lipolysis is used for body and face contouring due to its minimal invasiveness and cost-effectiveness, but related complications such as nontuberculous mycobacterium infection significantly affect its clinical application.

AIMS

This study aimed to review the literature on NTM infection after injection lipolysis.

METHODS

We conducted a literature review of scientific journals published in Medline and PubMed up to September 2022 on patients with NTM skin and soft tissue infections. We used the keywords: nontuberculous mycobacterium, infection, injection lipolysis, and lipolytic solution in various combinations with the Boolean operators AND, OR, and NOT. Only articles available in English and full version publications were considered for this review. Here, we reviewed the relevant mechanisms and drugs for injectable lipolysis and analyzed the possible correlation between NTM infection and injection lipolysis. We also summarize methods for the diagnosis and treatment of NTM infections and present some perspectives on this therapy.

RESULTS

Many patients with NTM infections had a history of fat-related surgery or therapy. NTM infection after injection lipolysis may be related to inadequate disinfection and sterilization of injection equipment and clinical procedures, the unqualified medication itself and free fatty acids released during injection lipolysis. Currently, diagnosis and treatment of NTM infection after lipolysis injections remains challenging.

CONCLUSIONS

Injection lipolysis represents a helpful option for local fat reduction. Doctors should strictly abide by the aseptic operation standards and use qualified products for there is a correlation between skin and soft tissue infection of nontuberculous mycobacterium and injection lipolysis. Providers should understand the mechanism, indications, and associated risks of injection lipolysis when injecting fat-dissolving drugs to reduce localized fat.

摘要

背景

注射溶脂因其微创性和成本效益而用于身体和面部塑形,但诸如非结核分枝杆菌感染等相关并发症显著影响其临床应用。

目的

本研究旨在综述注射溶脂后非结核分枝杆菌感染的相关文献。

方法

我们对截至2022年9月在Medline和PubMed上发表的关于非结核分枝杆菌皮肤和软组织感染患者的科学期刊进行了文献综述。我们使用了关键词:非结核分枝杆菌、感染、注射溶脂、溶脂溶液,并以各种组合与布尔运算符AND、OR和NOT一起使用。本综述仅考虑英文且为完整版的文章。在此,我们回顾了可注射溶脂的相关机制和药物,并分析了非结核分枝杆菌感染与注射溶脂之间可能的相关性。我们还总结了非结核分枝杆菌感染的诊断和治疗方法,并对该疗法提出了一些观点。

结果

许多非结核分枝杆菌感染患者有脂肪相关手术或治疗史。注射溶脂后的非结核分枝杆菌感染可能与注射设备和临床操作的消毒灭菌不充分、药物本身不合格以及注射溶脂过程中释放的游离脂肪酸有关。目前,注射溶脂后非结核分枝杆菌感染的诊断和治疗仍然具有挑战性。

结论

注射溶脂是局部减脂的一种有效选择。由于非结核分枝杆菌皮肤和软组织感染与注射溶脂之间存在相关性,医生应严格遵守无菌操作标准并使用合格产品。在注射溶脂药物以减少局部脂肪时,医疗人员应了解注射溶脂的机制、适应症和相关风险。

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