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[继发性软骨肉瘤]

[Secondary chondrosarcoma].

作者信息

Karata D I

出版信息

Vopr Onkol. 1987;33(9):74-8.

PMID:3660758
Abstract

A retrospective evaluation of 101 cases of secondary chondrosarcoma was performed. The results of the analysis of X-ray data showed chondrosarcoma to develop from osteocartilaginous exostosis or chondroma (53 and 47 cases, respectively). (One case lacked roentgenologic data). The former pattern of tumor development prevailed in patients under 40 years of age, while the latter one was more frequently observed in the older age group (68% of cases in each age bracket). Secondary chondrosarcoma was most frequently localized to long tubular and flat bones (48 and 34 patients, 47.53 and 33.66%, respectively). Roentgenologic diagnosis of early stage secondary chondrosarcoma was extremely difficult. Histologic examination showed degree I cell anaplasia in most cases. Surgery is the main procedure of treatment of secondary chondrosarcoma. Relapses were observed only in patients who had undergone sparing operations. The smaller the extent of surgery, the higher relapse rate was registered. Fifteen patients (14.87%) died of tumor progression. Sparing procedures were performed in 14 of them (93.3%).

摘要

对101例继发性软骨肉瘤进行了回顾性评估。X线数据分析结果显示,软骨肉瘤分别由骨软骨瘤或软骨瘤发展而来(分别为53例和47例)。(1例缺乏放射学数据)。肿瘤发展的前一种模式在40岁以下患者中占主导,而后一种模式在老年组中更常见(每个年龄组中占68%的病例)。继发性软骨肉瘤最常发生于长管状骨和扁平骨(分别为48例和34例患者,占47.53%和33.66%)。早期继发性软骨肉瘤的放射学诊断极其困难。组织学检查显示大多数病例为I级细胞间变。手术是继发性软骨肉瘤的主要治疗手段。仅在接受保守手术的患者中观察到复发。手术范围越小,复发率越高。15例患者(14.87%)死于肿瘤进展。其中14例(93.3%)接受了保守手术。

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