早产儿疫苗接种的最新进展。
An update on vaccination in preterm infants.
机构信息
Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil; Centro Neonatal do Instituto da Criança e Adolescente do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil; Departamento Científico de Neonatologia, Sociedade Brasileira de Pediatria (SBP), São Paulo, SP, Brazil.
Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil; Maternidade Santa Joana, São Paulo, SP, Brazil; Departamento de Imunizações, Sociedade Brasileira de Pediatria (SBP), São Paulo, SP, Brazil.
出版信息
J Pediatr (Rio J). 2023 Mar-Apr;99 Suppl 1(Suppl 1):S81-S86. doi: 10.1016/j.jped.2022.12.004. Epub 2023 Jan 3.
OBJECTIVE
The objective of this article is to review the most current literature on vaccines, focusing on their safety, immunogenicity, and efficacy in preterm newborns, aiming to improve vaccine coverage in this population.
DATA SOURCE
Most recent scientific publications addressing the immunization of preterm newborns.
DATA SYNTHESIS
Despite its immunological immaturity, vaccination is well tolerated by preterm infants, and protective immune responses are observed, but some studies have shown that preterm infants undergo unjustified delays in their vaccination schedule.
CONCLUSIONS
Despite being widely recommended, the routine immunization of preterm infants is often delayed, putting this vulnerable population at risk for several diseases, many of which are preventable by immunization. Every effort should be made to develop universal guidelines that define the immunization of preterm infants.
目的
本文旨在回顾疫苗的最新文献，重点关注其在早产儿中的安全性、免疫原性和有效性，旨在提高该人群的疫苗接种率。
资料来源
最近发表的关于早产儿免疫接种的科学出版物。
资料综合
尽管早产儿的免疫不成熟，但疫苗接种能很好地耐受，可观察到保护性免疫反应，但一些研究表明，早产儿的疫苗接种时间表存在不合理的延迟。
结论
尽管广泛推荐，但早产儿的常规免疫接种经常被延迟，使这一脆弱人群面临多种疾病的风险，其中许多疾病可通过免疫接种预防。应尽一切努力制定通用指南，为早产儿的免疫接种做出定义。
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