Layer P, Singer M V, Eysselein V E
Abteilung für Gastroenterologie, Medizinische Universitätsklinik Essen.
Z Gastroenterol. 1987 Aug;25 Suppl 3:69-73.
In western civilization, circadian rhythms of the gastrointestinal tract are dominated by a digestive-interdigestive rhythm: During the day interdigestive activity is rare because of frequent meal intakes prior to termination of preceding fed states: in contrast, nocturnal activity is largely interdigestive. Digestive and interdigestive functions are characterized by specific and interactive motor and secretory activity patterns. When exogenous influences via food intake are prevented, additional, underlying, endogenous, circadian rhythms are observed that modulate gastric and intestinal motility in a characteristic fashion, possibly with tight links to the central nervous system. It is likely that disturbances of physiologic circadian modulation of gastrointestinal function may have pathogenic importance.
在西方文明中,胃肠道的昼夜节律受消化-消化间期节律主导:白天由于在前一进食状态结束前频繁进食,消化间期活动很少;相反,夜间活动主要是消化间期的。消化和消化间期功能的特点是具有特定且相互作用的运动和分泌活动模式。当通过食物摄入的外源性影响被阻断时,会观察到额外的、潜在的、内源性的昼夜节律,这些节律以一种特征性方式调节胃和肠道的蠕动,可能与中枢神经系统有紧密联系。胃肠道功能的生理昼夜调节紊乱可能具有致病重要性。