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一种新的调强放射治疗计划二次校验工具的初步评估。

Preliminary evaluation of a novel secondary check tool for intensity modulated radiotherapy treatment planning.

机构信息

Medical Physics Department, A.S.L. TO4, 10015 Ivrea (TO), Italy.

Radiotherapy Department, A.S.L. TO4, 10015 Ivrea (TO), Italy.

出版信息

Phys Med. 2023 Feb;106:102528. doi: 10.1016/j.ejmp.2023.102528. Epub 2023 Jan 5.

Abstract

PURPOSE

To evaluate the dosimetric accuracy of the Delta4 Insight (DI) secondary-check dosimetry system.

METHODS

Absolute dosimetry in reference conditions, output factors, percent depth doses normalized and off-axis dose profiles for different field sizes calculated by DI were compared with measurements. Dose calculations for 20 clinical IMRT/VMAT plans generated in the TPS using both AAA or AcurosXB algorithms were compared with measurements. The average difference between calculated and measured point dose in high-dose region was calculated for all cases. 3D dose measurements were performed in Delta4 Phantom+ and a comparison between calculated and measured dose distributions was performed by means of the gamma analysis with 3 %/2 mm criteria. The dose distributions calculated by DI for 20 IMRT/VMAT plans were compared with those calculated by the TPS.

RESULTS

The absolute dosimetry computed by DI showed dose value in agreement with the measured one within 0.3 %. The average differences between measured and calculated output factors were less than 2.5 %. The average PDD differences were less than 0.6 %. An excellent agreement between calculations and off-axis measurements is found. The point doses calculated for the 20 recalculated plan showed good agreement with measurements with average differences less than 0.5 %. The average gamma pass rate values for the Delta4 Phantom + 3D dose analysis was greater than 97.%. The comparison of DI with theTPS showed good agreement for the used metrics.

CONCLUSIONS

Delta4 Insight may provide a useful independent secondary dose verification system for IMRT/VMAT plans, complementing the traditional global QA protocols.

摘要

目的

评估 Delta4 Insight(DI)二次核查剂量系统的剂量学准确性。

方法

通过 DI 计算的参考条件下的绝对剂量、输出因子、归一化的百分深度剂量和不同射野大小的离轴剂量分布与测量结果进行比较。比较了在 TPS 中使用 AAA 或 AcurosXB 算法生成的 20 个临床 IMRT/VMAT 计划的剂量计算与测量结果。对于所有情况,计算和测量的高剂量区域的点剂量之间的平均差异。在 Delta4 Phantom+中进行了 3D 剂量测量,并通过 3%/2mm 的伽马分析标准对计算和测量的剂量分布进行了比较。比较了 DI 对 20 个 IMRT/VMAT 计划的剂量分布计算结果与 TPS 的计算结果。

结果

DI 计算的绝对剂量值与测量值的偏差在 0.3%以内。测量和计算的输出因子之间的平均差异小于 2.5%。平均 PDD 差异小于 0.6%。计算和离轴测量之间具有极好的一致性。20 个重新计算的计划的点剂量计算与测量结果具有良好的一致性,平均差异小于 0.5%。Delta4 Phantom+3D 剂量分析的平均伽马通过率大于 97%。DI 与 TPS 的比较结果表明,对于使用的指标,两者具有良好的一致性。

结论

Delta4 Insight 可为 IMRT/VMAT 计划提供有用的独立二次剂量验证系统,补充传统的全局 QA 协议。

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