Department of Physical Therapy, Niigata University of Health and Welfare, Niigata 950-3198, Japan.
Department of Nutrition Service, NTT Medical Center Tokyo, Tokyo 141-8625, Japan.
Nutrients. 2022 Dec 26;15(1):113. doi: 10.3390/nu15010113.
Interventions for stroke-related sarcopenia in patients with stroke are needed, but the details of the target population are unclear. This systematic review aimed to identify trajectories of the prevalence of sarcopenia in the pre- and post-stroke periods and to determine the diagnostic criteria used in patients with stroke. We searched for literature in six databases: MEDLINE, EMBASE, Web of Science, Cochrane Central Register of Controlled Trials, CINAHL, and Ichushi-web (in Japanese). We included 1627 studies in the primary screening, and 35 studies were finally included. Of the 35 studies, 32 (91.4%) included Asian patients, and the criteria of the Asian Working Group for Sarcopenia was mainly used as the diagnostic criteria. Nineteen studies used muscle strength and muscle mass to diagnose sarcopenia, whereas a full assessment, including physical performance, was performed in five studies. The estimated prevalences of sarcopenia in pre-stroke, within 10 days of stroke, and from 10 days to 1 month after stroke were 15.8%, 29.5%, and 51.6%, respectively. Sarcopenia increased by approximately 15% from pre-stroke to 10 days, and increased by approximately 20% from 10 days to 1 month. Healthcare providers should note that the prevalence of sarcopenia increases during the acute phase in patients with stroke.
需要针对脑卒中相关肌少症的干预措施，但目标人群的具体情况尚不清楚。本系统评价旨在确定脑卒中患者在脑卒中前和脑卒中后时期肌少症的患病率变化轨迹，并确定用于脑卒中患者的诊断标准。我们在六个数据库中检索文献：MEDLINE、EMBASE、Web of Science、Cochrane 对照试验中心注册库、CINAHL 和 Ichushi-web（日文）。我们在初步筛选中纳入了 1627 项研究，最终纳入了 35 项研究。在这 35 项研究中，有 32 项（91.4%）纳入了亚洲患者，并且主要使用亚洲肌少症工作组的标准作为诊断标准。19 项研究使用肌肉力量和肌肉质量来诊断肌少症，而 5 项研究则进行了全面评估，包括身体机能。脑卒中前、脑卒中后 10 天内和脑卒中后 1 至 1 个月的肌少症患病率分别为 15.8%、29.5%和 51.6%。从脑卒中前到 10 天，肌少症的患病率增加了约 15%，从 10 天到 1 个月，肌少症的患病率增加了约 20%。医疗保健提供者应注意，在脑卒中患者的急性期，肌少症的患病率会增加。
