Sedaghat A, Ardehali S M, Sadigh M, Buxton M
J Trop Med Hyg. 1978 Oct;81(10):204-7.
To determine the prevalence of infection with Toxoplasma gondii in the Fars Province of Iran, sera from 300 patients hospitalised at the Pahlavi University Medical Centre in Shiraz were tested. There were 157 males and 143 females, with a mean age of 39 years (range 10--80 years). The indirect immunofluorescent antibody technique was used and titres of 1:16 and above were considered positive. Eighty eight patients of whom 50 were male and 38 female (mean age 41 years, range 14--80 years) had positive sera. Of these 88 patients, 35 (40%), 25 (28%), 17 (19%), 5 (6%) and 6 (7%) had antibody titres of 1:16, 1:32, 1:64, 1:128 and 1:256 respectively. One hundred and twenty three of the 212 patients with negative sera (58%) had contact with cats. A similar proportion of patients with positive sera [51 of 88 (58%)] also had contact with cats. It is concluded that a substantial proportion of our patients (29%) show serological evidence of infection with Toxoplasma gondii. A significant correlation between exposure to cats and the consumption of improperly cooked meat on the one hand and seropositivity on the other, could not be demonstrated. There was no significant increase in the incidence of seropositivity with increasing age (P = 0.35).
为确定伊朗法尔斯省弓形虫感染的患病率，对设拉子帕列维大学医学中心收治的300例患者的血清进行了检测。其中男性157例，女性143例，平均年龄39岁（范围10 - 80岁）。采用间接免疫荧光抗体技术，滴度为1:16及以上者被视为阳性。88例患者血清呈阳性，其中男性50例，女性38例（平均年龄41岁，范围14 - 80岁）。在这88例患者中，抗体滴度分别为1:16、1:32、1:64、1:128和1:256的患者有35例（40%）、25例（28%）、17例（19%）、5例（6%）和6例（7%）。212例血清阴性患者中有123例（58%）与猫有接触。血清阳性患者中也有相似比例[88例中的51例（58%）]与猫有接触。得出的结论是，我们的患者中有很大一部分（29%）显示出弓形虫感染的血清学证据。未证实接触猫和食用未煮熟肉类一方面与血清阳性另一方面之间存在显著相关性。血清阳性发生率并未随年龄增长而显著增加（P = 0.35）。
