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一项关于破裂前交通动脉瘤的支架辅助弹簧圈栓塞术与单纯弹簧圈栓塞术的单中心大样本量对比研究:基于倾向评分匹配的安全性、有效性及预后分析

A single-center comparative study with large sample size on stent-assisted coiling versus coiling alone for the ruptured anterior communicating artery aneurysms: Analysis of safety, efficacy, and prognosis based on propensity score matching.

作者信息

Shang Wei, Chang Xiaoting, Xu Yousong, Dong Bin

机构信息

Dalian Medical University, Dalian, Liaoning Province, China.

Department of Neurology, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.

出版信息

Interv Neuroradiol. 2025 Feb;31(1):71-79. doi: 10.1177/15910199221150293. Epub 2023 Jan 8.

Abstract

OBJECTIVE

To compare the safety, efficacy, and prognosis of stent-assisted coiling (SAC) versus coiling alone (CA) in the treatment of ruptured anterior communicating artery aneurysms (ACoAAs).

METHODS

The clinical and follow-up data of ruptured ACoAAs treated with endovascular treatment in our center from January 2011 to January 2021 were retrospectively collected. Patients were divided into an SAC group and a CA group based on whether stents were used, after which the two groups were matched for propensity scores. The general clinical data, embolization effect, perioperative complications, clinical, and follow-up results after matching were compared.

RESULTS

A total of 354 patients were enrolled, of whom 147 patients (41.5%) received SAC and the rest received CA. Comparison baseline of two groups showed that patients with a larger diameter, wide neck, irregular morphology, and anterior direction were more likely to receive SAC. After propensity score matching, 113 patients were included in each group. Immediately postoperative angiography results showed that the complete embolization rate of patients in the SAC group was significantly lower than that in the CA group (62.8% vs. 76.1%, p = 0.03). There were no significant differences between the two groups in the incidence of perioperative complications, mortality, poor prognosis at discharge or follow-up, mid-term complete occlusion rate and recurrence rate.

CONCLUSION

The stent-assisted treatment of ruptured ACoAAs did not increase the risk of perioperative complications or the probability of poor prognosis, indicating that SAC treatment of ruptured ACoAAs is safe and feasible and has a reliable mid-term cure rate.

摘要

目的

比较支架辅助弹簧圈栓塞术(SAC)与单纯弹簧圈栓塞术(CA)治疗破裂前交通动脉瘤(ACoAA)的安全性、有效性及预后。

方法

回顾性收集2011年1月至2021年1月在本中心接受血管内治疗的破裂ACoAA患者的临床及随访资料。根据是否使用支架将患者分为SAC组和CA组,然后对两组进行倾向得分匹配。比较匹配后的一般临床资料、栓塞效果、围手术期并发症、临床及随访结果。

结果

共纳入354例患者,其中147例(41.5%)接受SAC治疗,其余接受CA治疗。两组比较基线显示,直径较大、颈宽、形态不规则及向前指向的患者更有可能接受SAC治疗。倾向得分匹配后,每组纳入113例患者。术后即刻血管造影结果显示,SAC组患者的完全栓塞率显著低于CA组(62.8%对76.1%,p = 0.03)。两组在围手术期并发症发生率、死亡率、出院或随访时的不良预后、中期完全闭塞率及复发率方面无显著差异。

结论

支架辅助治疗破裂ACoAA并未增加围手术期并发症风险或不良预后的可能性,表明SAC治疗破裂ACoAA是安全可行的,且中期治愈率可靠。

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Stent assisted embolization of 64 anterior communicating artery aneurysms.支架辅助栓塞治疗 64 例前交通动脉瘤。
J Neurointerv Surg. 2013 Nov;5 Suppl 3:iii62-5. doi: 10.1136/neurintsurg-2012-010503. Epub 2012 Sep 21.

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