Nemes Attila, Kormányos Árpád, Rácz Gergely, Ruzsa Zoltán, Ambrus Nóra, Lengyel Csaba
Department of Medicine, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
Quant Imaging Med Surg. 2023 Jan 1;13(1):121-132. doi: 10.21037/qims-22-88. Epub 2022 Nov 16.
Three-dimensional speckle-tracking echocardiography (3DSTE) is a relatively new non-invasive imaging modality with ability for simultaneous chamber quantifications and determination of valvular dimensions. The aim of the present retrospective cohort study was to determine normal reference values of 3DSTE-derived tricuspid annular (TA) dimensions and functional properties and to evaluate their age- and gender dependency.
The present study comprised 156 healthy adult subjects, from which 28 cases were excluded due to inferior image quality, therefore the remaining group consisted of 128 cases with the mean age of 35.4±12.5 years (72 males). The subject population was further divided into the following categories: 18-29 years (n=57; mean age: 25.2±2.8 years, 51 males), 30-39 years (n=29; mean age: 34.1±2.5 years, 31 males), 40-49 years (n=17; mean age: 44.1±3.2 years, 11 males) and ≥50 years of age (n=25, mean age: 59.2±6.4 years, 14 males).
End-diastolic TA diameter (2.2±0.3 2.5±0.3 cm, P<0.05), area (7.1±1.3 8.1±1.7 cm, P<0.05) and perimeter (10.3±0.9 11.0±1.2 cm, P<0.05) were lower in females than in males in the 18-29 year-old group and TA area (6.1±0.8 8.0±1.2 cm, P<0.05) and TA perimeter (9.7±0.8 11.0±0.9 cm, P<0.05) were lower in females than in males in the 40-49 year-old group. End-systolic TA diameter were lower in females than in males in the 18-29 year-old group (1.8±0.2 1.9±0.3 cm, P<0.05) and TA area (4.7±0.3 6.3±1.2 cm, P<0.05) and TA perimeter (8.6±0.4 9.5±0.9 cm, P<0.05) were lower in females than in males in the 40-49 year-old group. TA fractional area change was found to be reduced in the 40-49 year-old group as compared to the 30-39 year-old group (21.7%±8.7% 29.2%±10.0%, P<0.05).
3DSTE is a novel method for non-invasive assessment of TA dimensions and functional properties. Results highlight the importance of age- and gender-specific reference values in case of TA diameter, area and perimeter and calculated functional features respecting the cardiac cycle.
三维斑点追踪超声心动图（3DSTE）是一种相对较新的无创成像方式，能够同时对心腔进行定量分析并测定瓣膜尺寸。本回顾性队列研究的目的是确定3DSTE得出的三尖瓣环（TA）尺寸和功能特性的正常参考值，并评估其年龄和性别依赖性。
本研究纳入156名健康成年受试者，其中28例因图像质量欠佳被排除，因此其余组由128例组成，平均年龄为35.4±12.5岁（72名男性）。受试者群体进一步分为以下类别：18 - 29岁（n = 57；平均年龄：25.2±2.8岁，51名男性）、30 - 39岁（n = 29；平均年龄：34.1±2.5岁，31名男性）、40 - 49岁（n = 17；平均年龄：44.1±3.2岁，11名男性）和≥50岁（n = 25，平均年龄：59.2±6.4岁，14名男性）。
在18 - 29岁组中，女性舒张末期TA直径（2.2±0.3对2.5±0.3 cm，P < 0.05）、面积（7.1±1.3对8.1±1.7 cm，P < 0.05）和周长（10.3±0.9对11.0±1.2 cm，P < 0.05）均低于男性；在40 - 49岁组中，女性TA面积（6.1±0.8对8.0±1.2 cm，P < 0.05）和TA周长（9.7±0.8对11.0±0.9 cm，P < 0.05）低于男性。在18 - 29岁组中，女性收缩末期TA直径低于男性（1.8±0.2对1.9±0.3 cm，P < 0.05）；在40 - 49岁组中，女性TA面积（4.7±0.3对6.3±1.2 cm，P < 0.05）和TA周长（8.6±0.4对9.5±0.9 cm，P < 0.05）低于男性。与30 - 39岁组相比，40 - 49岁组TA面积变化分数降低（21.7%±8.7%对29.2%±10.0%，P < 0.05）。
3DSTE是一种用于无创评估TA尺寸和功能特性的新方法。结果强调了在TA直径、面积和周长以及计算得出的心动周期功能特征方面，年龄和性别特异性参考值的重要性。
