Horn Thorsten, Narov Kalin D, Panfilio Kristen A
Adv Genet (Hoboken). 2022 Sep 12;3(3):2270031. doi: 10.1002/ggn2.202270031. eCollection 2022 Sep.
dsRNA Uptake In article 2100064 by Kristen A. Panfilio and co-workers, the cuticle exoskeleton of flour beetle larvae reveals normal anatomy (above: head-to-tail in blue-to-red) and long-term parental RNAi knockdown (below), here showing a mirror-image duplication of the abdomen (red termini to yellow center). Strong knockdown can persist for months despite transmission of full-length double-stranded RNA (dsRNA) from the mother into the egg, depleting maternal dsRNA levels.
双链RNA摄取 在克里斯汀·A·潘菲利奥及其同事发表的第2100064号文章中，面粉甲虫幼虫的角质层外骨骼显示出正常的解剖结构（上图：从蓝色头部到红色尾部）和长期的亲代RNA干扰敲低（下图），此处显示腹部的镜像重复（从红色末端到黄色中心）。尽管全长双链RNA（dsRNA）从母体传递到卵中，导致母体dsRNA水平耗尽，但强烈的敲低仍可持续数月。
