Catikkas Nezahat Muge, Erdogan Tugba Obekli, Reginster Jean Yves, Oren Meryem Merve, Aydin Caglar Ozer, Sacar Duygu Erbas, Ozkok Serdar, Kilic Cihan, Karan Mehmet Akif, Bahat Gulistan
Division of Geriatrics, Department of Internal Medicine, Istanbul Medical School, Istanbul University, Capa, 34093, Istanbul, Turkiye.
Department of Public Health, Epidemiology and Health Economics, Liège Medical School, University of Liège, Liège, Belgium.
Curr Aging Sci. 2023;16(2):133-142. doi: 10.2174/1874609816666230109153424.
Falls are a common public health problem in older adults regarding increased morbidity, mortality, and healthcare costs. Determining the factors associated with falls is of utmost importance for detecting at risk people. We present here a field study conducted to examine the prevalence of falls and the associated factors among community-dwelling older adults.
In this population-based cross-sectional study, we included adults aged > 60 years living in the Fatih District of the Istanbul Province between November 2014-May 2015, through a simple random sampling method. We noted age, sex, falls, fear of falling, number of diseases and medications, the presence of diabetes, hypertension, dyslipidemia, urinary and fecal incontinence, and chronic pain. Frailty was assessed with the FRAIL questionnaire. Functional capacity was evaluated by Katz's 6-item ADL and Lawton Brody's 8-item IADL scales. The European quality-5 dimension (EQ-5D) questionnaire was used for the quality of life assessment. The cognitive status screening was conducted with a Mini-cog test. Depressive mood was evaluated with the Geriatric Depression scale short form (GDS-SF). Malnutrition screening was conducted by the mini-nutritional assessment short form. Handgrip strength (HGS) was measured with a hand dynamometer. Body composition was assessed through a bioimpedance analysis. The 4-meter usual gait speed was recorded. The European Working Group on Sarcopenia in Older People2 (EWSGOP2) criteria was used for the sarcopenia definition. The Romberg and the postural instability tests were evaluated for balance and gait. Continuous variables were expressed as mean ± standard deviation or median and interquartile range for descriptive statistics, while categorical variables were expressed as the number and percentages. The differences between groups were determined through an independent sample t-test or Mann-Whitney U test when required, and Chi-square and Fisher's exact tests were applied for categorical variables. A multivariate logistic regression analysis was used to determine the independent factors associated with falls among the factors identified as significant in univariate analyses.
The prevalence of falls was 28.5% [mean age: 75.4 ± 7.3 (range: 61-101 years), 53.6% female], and a significant association was identified between falls and the number of diseases and medications, diabetes, chronic pain, frailty, ADL, IADL, and EQ-5D scores, dementia, GDS-SF score and level of ambulation in univariate analyses (p = 0.001, 0.030, 0.030, 0.010, 0.004, 0.040, 0.007, 0.003, 0.030 and 0.007, respectively). In the multivariate analysis, positive dementia (OR = 3.66, 95% CI = 1.40-9.53; p = 0.010) and frailty screenings (OR =1.47, 95% CI = 1.05-2.06; p = 0.020) were identified as associates of falls.
Falls were independently associated with positive dementia and frailty screening. These results will help develop specific and tailored precautions for at-risk groups to prevent the negative outcomes of falls.
跌倒在老年人中是一个常见的公共卫生问题,会增加发病率、死亡率和医疗成本。确定与跌倒相关的因素对于识别高危人群至关重要。我们在此展示一项实地研究,旨在调查社区居住老年人中跌倒的患病率及相关因素。
在这项基于人群的横断面研究中,我们于2014年11月至2015年5月期间,通过简单随机抽样方法纳入了居住在伊斯坦布尔省法提赫区的60岁以上成年人。我们记录了年龄、性别、跌倒情况、害怕跌倒、疾病和药物数量、糖尿病、高血压、血脂异常、大小便失禁以及慢性疼痛的情况。使用FRAIL问卷评估衰弱情况。通过Katz的6项日常生活活动能力量表和Lawton Brody的8项工具性日常生活活动能力量表评估功能能力。使用欧洲五维度健康量表(EQ - 5D)问卷进行生活质量评估。通过简易认知测试进行认知状态筛查。使用老年抑郁量表简表(GDS - SF)评估抑郁情绪。通过简易营养评估简表进行营养不良筛查。使用握力计测量握力。通过生物电阻抗分析评估身体成分。记录4米常规步态速度。使用老年人肌少症欧洲工作组2(EWSGOP2)标准定义肌少症。评估Romberg试验和姿势不稳试验以检测平衡和步态。连续变量以均值±标准差或中位数及四分位间距表示用于描述性统计,分类变量以数量和百分比表示。必要时,通过独立样本t检验或Mann - Whitney U检验确定组间差异,对于分类变量应用卡方检验和Fisher精确检验。使用多因素逻辑回归分析确定在单因素分析中被确定为显著的因素中与跌倒相关的独立因素。
跌倒的患病率为28.5%[平均年龄:75.4±7.3(范围:61 - 101岁),女性占53.6%],在单因素分析中,跌倒与疾病和药物数量、糖尿病、慢性疼痛、衰弱、日常生活活动能力量表、工具性日常生活活动能力量表和EQ - 5D评分、痴呆、GDS - SF评分以及行走能力水平之间存在显著关联(分别为p = 0.001、0.030、0.030、0.010、0.004、0.040、0.007、0.003、0.030和0.007)。在多因素分析中,阳性痴呆(比值比[OR]=3.66,95%置信区间[CI]=1.40 - 9.53;p = 0.010)和衰弱筛查(OR = 1.47,95% CI = 1.05 - 2.06;p = 0.020)被确定为跌倒的相关因素。
跌倒与阳性痴呆和衰弱筛查独立相关。这些结果将有助于为高危人群制定具体且针对性的预防措施,以防止跌倒带来的负面后果。