Winslow Nolan, Olson Elsa, Martin Ryan, Ivankovic Sven, Garst Jonathan, Maldonado Andres
Department of Neurosurgery, OSF Saint Francis Medical Center, 530 NE Glen Oak Avenue, Peoria, IL, 61637, USA.
University of Illinois College of Medicine at Peoria, Peoria, IL, USA.
Neurosurg Rev. 2023 Jan 11;46(1):35. doi: 10.1007/s10143-022-01939-5.
Cerebellar ischemic stroke (CIS) is a morbid neurological event, with potentially fatal consequences. There is currently no objective standard of care regarding when surgical procedures are required for this entity. We retrospectively reviewed 763 patients with CIS, 247 patients of which had a stroke larger than 1 cm in greatest dimension on cranial imaging. In this subgroup, 11% of patients received ventriculostomy, 12% suboccipital craniectomy, and 9% mechanical endovascular thrombectomy. Various clinical and radiographic variables were examined for relationship to surgical procedures, 30-day mortality rate, and modified Rankin scores. The smallest volume of stroke requiring a surgical procedure was 15.5 mL (BrainLab Software). Patients receiving surgical procedures had a higher incidence of multi-territory infarctions, hydrocephalus, cistern compression, 4th ventricular compression, as well as younger age, lower admission GCS, higher admission NIHSS, and higher 30-day mortality/disability. Patients deemed to require surgical procedures for CIS have a higher expected morbidity and mortality than those not requiring surgery. Various clinical and radiographic variables, including stroke volume, can be used to guide selection of patients requiring surgery.
小脑缺血性卒中(CIS)是一种严重的神经学事件,可能会导致致命后果。目前对于该病症何时需要进行外科手术尚无客观的治疗标准。我们回顾性分析了763例CIS患者,其中247例患者的颅脑影像学检查显示最大径大于1厘米的卒中。在这个亚组中,11%的患者接受了脑室造瘘术,12%接受了枕下颅骨切除术,9%接受了机械性血管内血栓切除术。我们研究了各种临床和影像学变量与手术方式、30天死亡率以及改良Rankin评分之间的关系。需要进行外科手术的最小卒中体积为15.5毫升(BrainLab软件)。接受手术的患者多区域梗死、脑积水、脑池受压、第四脑室受压的发生率更高,同时年龄更小、入院时格拉斯哥昏迷评分更低、入院时美国国立卫生研究院卒中量表评分更高,30天死亡率/残疾率也更高。被认为需要进行CIS手术的患者比不需要手术的患者预期发病率和死亡率更高。各种临床和影像学变量,包括卒中体积,可用于指导需要手术的患者的选择。