Division of Thoracic Surgery, The Thoracic Surgery Oncology Laboratory and the International Mesothelioma Program, Lung Center, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts, USA.
J Surg Oncol. 2023 Feb;127(2):343-354. doi: 10.1002/jso.27152.
The surgical management of pleural mesothelioma (PM) can be divided into diagnostic, staging, palliation, and cytoreductive surgery. In the cytoreductive surgical setting, the combination of different treatment modalities has led to better outcomes than surgery alone. The scarcity of high-quality studies has led to heterogeneity in management of PM across the mesothelioma treatment centers. Here, we review the literature regarding the most important open questions and ongoing clinical trials.
胸膜间皮瘤(PM)的手术治疗可分为诊断、分期、姑息治疗和细胞减灭术。在细胞减灭手术环境中,不同治疗方式的联合应用导致了比单独手术更好的结果。由于高质量研究的缺乏,导致了间皮瘤治疗中心在 PM 管理方面存在异质性。在这里,我们回顾了关于最重要的开放性问题和正在进行的临床试验的文献。