Wu Xianyuan, De Bruyn Mario, Barta Katalin
University of Groningen Stratingh Institute for Chemistry Groningen The Netherlands.
University of Graz Department of Chemistry, Organic and Bioorganic Chemistry Heinrichstraße 28/II 8010 Graz Austria.
Chem Ing Tech. 2022 Nov;94(11):1808-1817. doi: 10.1002/cite.202200091. Epub 2022 Sep 19.
Diamines are important industrial chemicals. In this paper we outline the feasibility of lignocellulose as a source of diol-containing molecules. We also illustrate the possibility of turning these diols into their diamines in good to excellent yields. Central to these transformations is the use of commercially available Raney Ni. For diol formation, the Raney Ni engages in hydrogenation and often also demethoxylation, that way funneling multiple components to one single molecule. For diamine formation, Raney Ni catalyzes hydrogen-borrowing mediated diamination in the presence of NH.
二胺是重要的工业化学品。在本文中，我们概述了木质纤维素作为含二醇分子来源的可行性。我们还说明了将这些二醇以良好至优异的产率转化为其二胺的可能性。这些转化的核心是使用市售的雷尼镍。对于二醇的形成，雷尼镍参与氢化反应，并且常常还进行脱甲氧基化反应，通过这种方式将多种成分汇聚到一个单一分子中。对于二胺的形成，雷尼镍在NH存在下催化借氢介导的胺化反应。
