Jeon Won Jin, Mehta Akhil, Hudson Jessica, Castillo Dani Ran, Wang Jun, Nguyen Anthony, Akhtari Mojtaba
Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
Department of Anatomic and Clinical Pathology, Loma Linda University Medical Center, Loma Linda, CA, USA.
Am J Med Sci. 2023 May;365(5):457-461. doi: 10.1016/j.amjms.2023.01.002. Epub 2023 Jan 9.
Deep venous thrombosis (DVT) is a complication of myeloproliferative neoplasms (MPNs). However, DVTs in unusual sites such as portal vein thrombosis (PVT) are rare and may be the first clinical manifestation of occult MPNs. There is a need for increasing awareness of such manifestations; so, here we discuss a patient who presented with new portal vein thrombosis, underwent further studies, was ultimately diagnosed with JAK2 positive MPN, and started on appropriate treatment with improvement of thrombosis and controlled hematocrit.
深静脉血栓形成（DVT）是骨髓增殖性肿瘤（MPN）的一种并发症。然而，诸如门静脉血栓形成（PVT）等不常见部位的DVT较为罕见，且可能是隐匿性MPN的首发临床表现。有必要提高对这类表现的认识；因此，我们在此讨论一位出现新发门静脉血栓形成的患者，该患者接受了进一步检查，最终被诊断为JAK2阳性MPN，并开始接受适当治疗，血栓形成情况得到改善，血细胞比容得到控制。
