Monk Steve H, O'Brien Matthew, Perle Stephen, Bohl Michael, Finger Frederick, Chewning Samuel J, Holland Christopher M
Atrium Health Neurological Surgery, Charlotte, NC, USA.
Carolina Neurosurgery & Spine Associates, Charlotte, NC, USA.
Int J Spine Surg. 2023 Apr;17(2):258-264. doi: 10.14444/8417. Epub 2023 Jan 12.
Anterior cervical corpectomy and fusion (ACCF) is often required to adequately decompress the spinal cord in patients with multilevel cervical spondylosis. Unfortunately, multilevel corpectomy constructs have high rates of early failure and frequently require supplemental posterior fixation. First described in 2003, skip ACCF (sACCF) is defined by corpectomies above and below an intervening vertebral body, which serves as an additional fixation point to augment biomechanical stability. Subsequent studies report high fusion rates and low construct failure rates secondary to superior biomechanical stability.
The goal of this study was to demonstrate the safety and efficacy of sACCF in the largest series published to date.
This study was a retrospective case series of all patients who underwent sACCF at a single institution over a 10-year period. Standard demographic and perioperative data were collected. Outcome data included immediate postoperative complications, long-term reoperation, and pre- and postoperative radiographic parameters.
Forty-five patients underwent sACCF: 42 at C4-C6 and 3 at C5-C7. Mean age was 57.5 years. More than half (64.4%) of patients were smokers. Almost all patients were discharged home, the vast majority (82.2%) within 3 days of surgery. Five patients (11.1%) developed complications during the index hospitalization: 2 C5 palsies and 3 medical complications. Three patients (6.7%) developed instrumentation failure requiring anterior revision and supplemental posterior fixation. There were statistically significant increases in C1-C7 (47.8 vs 41.1, < 0.001) and C2-C7 lordosis (11.1 vs 5.0, < 0.001) on postoperative radiographs compared with preoperative imaging. Average follow-up was 21.1 months.
sACCF can be performed safely with complication rates similar to those reported for multilevel anterior cervical discectomy and fusion or adjacent segment ACCF. It should be considered for patients with multilevel cervical pathology for whom an anterior approach is favored.
sACCF is an effective surgical technique for multilevel cervical decompression and correction of cervical alignment.
对于多节段颈椎病患者,常常需要进行颈椎前路椎体次全切除融合术(ACCF)以充分减压脊髓。不幸的是,多节段椎体次全切除结构早期失败率较高,且常常需要补充后路固定。跳跃式ACCF(sACCF)于2003年首次被描述,其定义为在一个中间椎体的上方和下方进行椎体次全切除,该中间椎体作为一个额外的固定点以增强生物力学稳定性。随后的研究报告称,由于具有更好的生物力学稳定性,其融合率高且结构失败率低。
本研究的目的是在迄今为止发表的最大系列病例中证明sACCF的安全性和有效性。
本研究是一项回顾性病例系列研究,纳入了在10年期间于单一机构接受sACCF的所有患者。收集了标准的人口统计学和围手术期数据。结果数据包括术后即刻并发症、长期再次手术以及术前和术后的影像学参数。
45例患者接受了sACCF:42例为C4 - C6节段,3例为C5 - C7节段。平均年龄为57.5岁。超过一半(64.4%)的患者为吸烟者。几乎所有患者均出院回家,绝大多数(82.2%)在术后3天内出院。5例患者(11.1%)在首次住院期间出现并发症:2例发生C5麻痹,3例出现内科并发症。3例患者(6.7%)出现内固定失败,需要进行前路翻修和补充后路固定。与术前影像学相比,术后X线片显示C1 - C7前凸(47.8°对41.1°,<0.001)和C2 - C7前凸(11.1°对5.0°,<0.001)有统计学意义的增加。平均随访时间为21.1个月。
sACCF可以安全地进行,其并发症发生率与多节段颈椎间盘切除融合术或相邻节段ACCF报告的发生率相似。对于倾向于采用前路手术的多节段颈椎病变患者,应考虑采用sACCF。
sACCF是一种有效的手术技术,可用于多节段颈椎减压和颈椎对线矫正。