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年龄对宫颈癌预后的影响。

The influence of age on prognosis in carcinoma of the cervix.

作者信息

Smales E, Perry C M, Ashby M A, Baker J W

机构信息

Department of Radiotherapy and Oncology, Royal Marsden Hospital, Sutton, Surrey, London.

出版信息

Br J Obstet Gynaecol. 1987 Aug;94(8):784-7. doi: 10.1111/j.1471-0528.1987.tb03727.x.

DOI:10.1111/j.1471-0528.1987.tb03727.x
PMID:3663534
Abstract

Of 385 new patients with invasive carcinoma of the cervix FIGO stages IB-IV treated between 1970-1984 inclusive, 11% (43 patients) were aged less than or equal to 35 years. During the period studied there was a gradual rise in the proportion of such young women from 2% for the triennium 1970-1972 to 18% for 1982-1984. In women aged less than or equal to 35 years early stage disease predominated, 72% presenting with stage IB disease, compared with 29% in the older age group. For FIGO stage IB there was no significant difference in actuarial survival between younger and older patients (P greater than 0.1), both age groups having a 5-year survival rate of 81%. Similarly for FIGO stage II there was no difference in actuarial survival (P greater than 0.1) between younger and older patients who had 5-year survival rates of 66% and 63% respectively. In our experience the incidence of invasive carcinoma of the cervix in young women is rising, but stage for stage their survival is similar to that of older women.

摘要

在1970年至1984年(含)期间接受治疗的385例国际妇产科联盟(FIGO)分期为IB-IV期的子宫颈浸润癌新患者中,11%(43例)年龄小于或等于35岁。在研究期间,这类年轻女性的比例逐渐上升,从1970 - 1972年三年期的2%升至1982 - 1984年的18%。年龄小于或等于35岁的女性中早期疾病占主导,72%为IB期疾病,而老年组这一比例为29%。对于FIGO IB期,年轻患者和老年患者的精算生存率无显著差异(P>0.1),两个年龄组的5年生存率均为81%。同样,对于FIGO II期,年轻患者和老年患者的精算生存率也无差异(P>0.1),他们的5年生存率分别为66%和63%。根据我们的经验,年轻女性子宫颈浸润癌的发病率正在上升,但逐期来看,她们的生存率与老年女性相似。

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引用本文的文献

1
Factors influencing tumor cell kinetics in cervical cancer.影响子宫颈癌肿瘤细胞动力学的因素。
J Cancer Res Clin Oncol. 1996;122(8):504-8. doi: 10.1007/BF01187164.
2
In vitro platinum drug chemosensitivity of human cervical squamous cell carcinoma cell lines with intrinsic and acquired resistance to cisplatin.对顺铂具有内在和获得性耐药性的人宫颈鳞状细胞癌细胞系的体外铂类药物化学敏感性
Br J Cancer. 1993 Aug;68(2):240-50. doi: 10.1038/bjc.1993.322.
3
Survival among women with cancer of the uterine cervix: influence of marital status and social class.
子宫颈癌女性的生存率:婚姻状况和社会阶层的影响。
J Epidemiol Community Health. 1990 Dec;44(4):293-6. doi: 10.1136/jech.44.4.293.