Smales E, Perry C M, Ashby M A, Baker J W
Department of Radiotherapy and Oncology, Royal Marsden Hospital, Sutton, Surrey, London.
Br J Obstet Gynaecol. 1987 Aug;94(8):784-7. doi: 10.1111/j.1471-0528.1987.tb03727.x.
Of 385 new patients with invasive carcinoma of the cervix FIGO stages IB-IV treated between 1970-1984 inclusive, 11% (43 patients) were aged less than or equal to 35 years. During the period studied there was a gradual rise in the proportion of such young women from 2% for the triennium 1970-1972 to 18% for 1982-1984. In women aged less than or equal to 35 years early stage disease predominated, 72% presenting with stage IB disease, compared with 29% in the older age group. For FIGO stage IB there was no significant difference in actuarial survival between younger and older patients (P greater than 0.1), both age groups having a 5-year survival rate of 81%. Similarly for FIGO stage II there was no difference in actuarial survival (P greater than 0.1) between younger and older patients who had 5-year survival rates of 66% and 63% respectively. In our experience the incidence of invasive carcinoma of the cervix in young women is rising, but stage for stage their survival is similar to that of older women.
在1970年至1984年(含)期间接受治疗的385例国际妇产科联盟(FIGO)分期为IB-IV期的子宫颈浸润癌新患者中,11%(43例)年龄小于或等于35岁。在研究期间,这类年轻女性的比例逐渐上升,从1970 - 1972年三年期的2%升至1982 - 1984年的18%。年龄小于或等于35岁的女性中早期疾病占主导,72%为IB期疾病,而老年组这一比例为29%。对于FIGO IB期,年轻患者和老年患者的精算生存率无显著差异(P>0.1),两个年龄组的5年生存率均为81%。同样,对于FIGO II期,年轻患者和老年患者的精算生存率也无差异(P>0.1),他们的5年生存率分别为66%和63%。根据我们的经验,年轻女性子宫颈浸润癌的发病率正在上升,但逐期来看,她们的生存率与老年女性相似。