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饮食与生活方式预防阿尔茨海默病和认知能力下降:A. G. 莱文森基金会会议论文集。

Prevention of Alzheimer's Disease and Cognitive Decline with Diet and Lifestyle: Proceedings of the A. G. Leventis Foundation Conference.

机构信息

Stefanos N. Kales, Department of Environmental Health, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA,

出版信息

J Prev Alzheimers Dis. 2023;10(1):137-143. doi: 10.14283/jpad.2022.99.

Abstract

The A. G. Leventis Foundation International Conference, "Prevention of Alzheimer's Disease and Cognitive Decline with Diet and Lifestyle", was held on May 11-12th, 2022 in Nicosia, Cyprus. This conference examined the role of diet and lifestyle for the prevention and treatment of Alzheimer's Disease and other forms of cognitive decline. Speakers from leading academic institutions presented evidence on healthy dietary patterns, with a particular focus on the traditional Mediterranean diet (MedDiet), in association with cognitive outcomes, mainly cognitive decline, dementia, and Alzheimer's disease, from both observational and interventional studies. Moreover, future directions for the potential use of olive oil, rich in polyphenols, for its therapeutic use as a nutraceutical, as well as nutritional interventions with high-quality dietary patterns (i.e. MedDiet) that support existing primarily observational evidence for the prevention of cognitive decline, as well as challenges in designing rigorous clinical trials are summarized and discussed within the conference proceedings.

摘要

“AG Leventis 基金会国际会议:饮食与生活方式预防阿尔茨海默病和认知能力下降”于 2022 年 5 月 11 日至 12 日在塞浦路斯尼科西亚举行。本次会议探讨了饮食和生活方式在预防和治疗阿尔茨海默病及其他形式认知能力下降方面的作用。来自顶尖学术机构的演讲者介绍了健康饮食模式的作用,特别关注了传统的地中海饮食(MedDiet)与认知结果之间的关系,主要是认知能力下降、痴呆和阿尔茨海默病,这涉及到观察性研究和干预性研究。此外,会议还总结和讨论了橄榄油作为一种具有治疗作用的营养保健品的潜在应用的未来方向,以及支持现有主要观察性证据的高质量饮食模式(即 MedDiet)的营养干预措施,以预防认知能力下降,以及在设计严格临床试验方面所面临的挑战。

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