Robertson J F, Imrie C W, Hole D J, Carter D C, Blumgart L H
Department of Surgery, Royal Infirmary, Glasgow, UK.
Br J Surg. 1987 Sep;74(9):816-9. doi: 10.1002/bjs.1800740921.
Forty-one patients presented to our hospital between 1959 and 1983 with periampullary carcinoma. Twenty-six (63 per cent) underwent radical surgery, eight (20 per cent) local excision of the tumour, six (15 per cent) had bypass procedures and one was treated by endoscopic sphincterotomy (2 per cent). Potentially curative resection was performed in 83 per cent of the 41 patients. The operative mortalities for radical, local and bypass surgery were 7.7 per cent, 25 per cent and 16.6 per cent respectively. The degree of tumour differentiation significantly affected survival while local spread did not significantly affect survival in patients treated radically. The 5 year survival rates (calculated actuarially) for radical, local and bypass surgery were 34, 44 and 0 per cent respectively.
1959年至1983年间，有41例患者因壶腹周围癌前来我院就诊。其中26例（63%）接受了根治性手术，8例（20%）进行了肿瘤局部切除，6例（15%）接受了旁路手术，1例（2%）接受了内镜括约肌切开术。41例患者中有83%接受了潜在根治性切除术。根治性手术、局部手术和旁路手术的手术死亡率分别为7.7%、25%和16.6%。肿瘤分化程度对生存率有显著影响，而局部扩散对接受根治性治疗的患者生存率无显著影响。根治性手术、局部手术和旁路手术的5年生存率（精算计算）分别为34%、44%和0%。
