Guangdong Provincial Key Laboratory of Photonics Information Technology, School of Information Engineering, Guangdong University of Technology, Guangzhou510006, China.
Institute of Nanophotonics, Jinan University, Guangzhou511443, China.
ACS Appl Mater Interfaces. 2023 Jan 25;15(3):4469-4476. doi: 10.1021/acsami.2c18412. Epub 2023 Jan 15.
Noninvasive and sensitive thermometry is crucial to human health monitoring and applications in disease diagnosis. Despite recent advances in optical temperature detection, the construction of sensitive wearable temperature sensors remains a considerable challenge. Here, a flexible and biocompatible optical temperature sensor is developed by combining plasmonic semiconductor WO enhanced upconversion emission (UCNPs/WO) with flexible poly(lactic acid) (PLA)-based optical fibers. The UCNPs/WO offers highly thermal-sensitive and obviously enhanced dual-wavelength emissions for ratiometric temperature sensing. The PLA polymer endows the sensor with excellent light-transmitting ability for laser excitation and emission collection and high biocompatibility. The fabricated UCNPs/WO-PLA sensor exhibits stable and rapid temperature response in the range 298-368 K, with a high relative sensitivity of 1.53% K and detection limit as low as ±0.4 K. More importantly, this proposed sensor is demonstrated to possess dual function on real-time detection for physiological thermal changes and heat release, exhibiting great potential in wearable health monitoring and biotherapy applications.
非侵入式和高灵敏度的测温技术对于人体健康监测和疾病诊断应用至关重要。尽管近年来在光学温度检测方面取得了进展,但构建敏感的可穿戴温度传感器仍然是一个巨大的挑战。在这里,通过将等离子体半导体 WO 增强上转换发射(UCNPs/WO)与柔性聚乳酸(PLA)基光纤相结合,开发了一种灵活且生物兼容的光学温度传感器。UCNPs/WO 提供了高度热敏和明显增强的双波长发射,用于比率温度传感。PLA 聚合物赋予传感器出色的透光能力,可用于激光激发和发射收集,并具有高生物相容性。所制备的 UCNPs/WO-PLA 传感器在 298-368 K 的范围内表现出稳定且快速的温度响应,相对灵敏度高达 1.53% K,检测限低至±0.4 K。更重要的是,该传感器还具有实时检测生理热变化和热释放的双重功能,在可穿戴健康监测和生物治疗应用中具有巨大的潜力。