Anjum Shamaa, Ahmed Nabeel, Ganapathy Dhanraj M, Maiti Subhabrata, Pandurangan Kiran Kumar
Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
J Adv Pharm Technol Res. 2022 Nov;13(Suppl 1):S223-S227. doi: 10.4103/japtr.japtr_380_22. Epub 2022 Nov 30.
D-dimer molecules are formed by the degradation of cross-linked fibrin during the process of fibrinolysis. The formation of D-dimer requires the activity of activated factor XIII (factor XIIIa), plasmin, and thrombin. To assess the awareness about D-dimer assay among dental students. A cross-sectional study was done among 100 dental practitioners through an online survey. The survey consisted of 10 semiclosed prevalidated and reliable questionnaires based on the knowledge, attitude, and practice of the dentists on D-dimer assay. Descriptive and inferential statistics were performed to report the responses of the participants. Most participants did not know what a D-dimer assay is (55%). Forty-six percent of participants responded that the D-dimer assay is used to rule out serious blood clots. Fifty-four percent of the participants responded that fibrin D-dimers are formed when fibrin strands are formed. The current study shows that the knowledge about D-dimer assay is more in CRRI than in participants of junior year of study. Thus, more rigorous educational programs should be initiated to further enrich the knowledge among dental students.
D - 二聚体分子是在纤维蛋白溶解过程中由交联纤维蛋白降解形成的。D - 二聚体的形成需要活化因子 XIII(因子 XIIIa)、纤溶酶和凝血酶的活性。为评估牙科学生对D - 二聚体检测的了解情况。通过在线调查对100名牙科从业者进行了横断面研究。该调查由10份基于牙医对D - 二聚体检测的知识、态度和实践的半封闭式预验证且可靠的问卷组成。进行描述性和推断性统计以报告参与者的回答。大多数参与者不知道什么是D - 二聚体检测(55%)。46%的参与者回答D - 二聚体检测用于排除严重血栓。54%的参与者回答当纤维蛋白链形成时会形成纤维蛋白D - 二聚体。当前研究表明,与大学低年级学生相比,牙科学院研究生对D - 二聚体检测的知识了解更多。因此,应启动更严格的教育计划以进一步丰富牙科学生的知识。