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阴茎保留术治疗局部晚期近端原发性尿道癌:技术与结局。

Phallus Preservation for Locally Advanced Proximal Primary Urethral Carcinoma: Technique and Outcomes.

机构信息

Department of Urology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.

Department of Urology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia; Institute of Academic Surgery, Royal Prince Alfred Hospital, Camperdown, NSW, Australia; Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.

出版信息

Urology. 2023 Mar;173:198-203. doi: 10.1016/j.urology.2022.12.034. Epub 2023 Jan 14.

Abstract

INTRODUCTION

To describe a novel method of penile sparing perineal urethrectomy for locally advanced proximal primary urethral cancers (PUC).

TECHNICAL CONSIDERATIONS

In mid-2021, 2 cases underwent pelvic exenterative surgery for pT3 and pT4 PUC. The procedure comprised of a complete urethrectomy, proximal penectomy, en bloc pubectomy and excision of pelvic diaphragm in both cases. One case included a wide excision of scrotum, whilst the other required a prostatectomy and abdominoperineal resection of the rectum to achieve complete tumor resection. A complete R0 resection was achieved in both cases. At 6 months follow up, there is no evidence of ischemic necrosis of the penis and cosmesis is satisfactory to both patients. We provide a comprehensive operative description of both cases, together with illustrations, and discuss the underlying principles of penile preservation in the surgical treatment of locally advanced proximal PUC.

CONCLUSION

Complete perineal urethrectomy with phallic preservation is feasible in men with locally advanced proximal bulbar urethral cancer in the absence of tumor invasion of the penile shaft. The remnant penis survives off arterial supply from the superficial penile arteries arising from the external pudendal arteries. Phallic preservation may benefit patient's psychological quality of life post-procedure.

摘要

简介

描述一种用于局部晚期近端原发性尿道癌(PUC)的新型阴茎保留会阴尿道切除术方法。

技术考虑因素

2021 年年中,2 例患者因 T3 和 T4 期 PUC 接受了盆腔切除术。该手术包括完全尿道切除术、近端阴茎切除术、整块耻骨联合切除术和骨盆横膈膜切除术。1 例包括阴囊广泛切除术,而另 1 例需要前列腺切除术和腹会阴直肠切除术才能实现完全肿瘤切除。在这两种情况下均达到了完全 R0 切除。在 6 个月的随访中,没有发现阴茎缺血性坏死的迹象,两名患者的美容效果均令人满意。我们提供了这两种情况的全面手术描述,包括插图,并讨论了在局部晚期近端 PUC 的手术治疗中保留阴茎的基本原则。

结论

在没有阴茎干肿瘤侵犯的情况下,对于局部晚期近端球部尿道癌的男性,完全会阴尿道切除术联合阴茎保留是可行的。残余阴茎的存活依赖于发自阴部外动脉的浅表阴茎动脉的动脉供应。阴茎保留可能有益于患者术后的生活质量。

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