Colimberti D, Mancino C, Notaro L, Pinzone F, Rinaldi A, Triolo G
Minerva Med. 1978 Oct 27;69(51):3515-8.
Anti-islet cell cytoplasm antibodies (ICA) were noted in the serum of insulin-dependent diabetics, but not in subjects with insulin-independent forms. These antibodies seem to represent an immunological marker for two forms of the disease, one in which ICA appears shortly after onset and later disappears, and another ("autoimmune") form in which ICA is detectable for long periods and persists along with other signs of alteration of the immune system.
在胰岛素依赖型糖尿病患者的血清中发现了抗胰岛细胞质抗体（ICA），而在非胰岛素依赖型患者中未发现。这些抗体似乎是该疾病两种形式的免疫标志物，一种形式是ICA在发病后不久出现，随后消失；另一种（“自身免疫性”）形式是ICA可长期检测到，并与免疫系统改变的其他迹象一起持续存在。
