Seo Chan, An Hyun Woo, Han Won, Lee Joo Won, Shrestha Krishna K, Jung Won-Kyo, Shin Joong Ho, Lee Sang Gil
Department of Food Science and Nutrition, Pukyong National University, 45 Yongso-Ro, Nam-Gu, Busan, 48513 Republic of Korea.
Department of Smart Green Technology Engineering, Pukyong National University, Busan, 48513 Republic of Korea.
Food Sci Biotechnol. 2022 Oct 2;32(2):221-228. doi: 10.1007/s10068-022-01175-z. eCollection 2023 Feb.
Pollutant exposure due to industrial development increases oxidative stress in human bodies. Dietary intake of antioxidant shows a protective effect against oxidative damage induced by oxidative stress. Therefore, the development of natural antioxidants is needed. In this study, the antioxidant activities of some Nepali medicinal plant extracts were measured. Using Rose bengal and 3,3',5,5'-tetramethylbenzidine, a novel assay was utilized to evaluate the singlet oxygen scavenging capacity, and showed a strong correlation with other antioxidant assays. Also, antioxidant capacities based on four assays including the singlet oxygen scavenging assay were highly correlated (≥ 0.858) with the total phenolic contents in the medicinal plant extracts. Among the selected extracts, , and showed the highest antioxidant capacities. Overall, this study presents a novel approach for evaluating singlet oxygen scavenging capacity, and performed a screening of antioxidant capacities of 54 Nepali herbal medicines.
The online version contains supplementary material available at 10.1007/s10068-022-01175-z.
工业发展导致的污染物暴露会增加人体的氧化应激。通过饮食摄入抗氧化剂对氧化应激诱导的氧化损伤具有保护作用。因此,需要开发天然抗氧化剂。在本研究中,对一些尼泊尔药用植物提取物的抗氧化活性进行了测定。使用孟加拉玫瑰红和3,3',5,5'-四甲基联苯胺,采用一种新的测定方法来评估单线态氧清除能力,该方法与其他抗氧化测定方法具有很强的相关性。此外,基于包括单线态氧清除测定在内的四种测定方法的抗氧化能力与药用植物提取物中的总酚含量高度相关(≥0.858)。在所选择的提取物中,[提取物名称未给出]、[提取物名称未给出]和[提取物名称未给出]表现出最高的抗氧化能力。总体而言,本研究提出了一种评估单线态氧清除能力的新方法,并对54种尼泊尔草药的抗氧化能力进行了筛选。
在线版本包含可在10.1007/s10068-022-01175-z获取的补充材料。