Zhonghua Yi Xue Za Zhi. 2023 Jan 17;103(3):167-170. doi: 10.3760/cma.j.cn112137-20220505-00991.
Irreversible electroporation ablation therapy can destroy tumor cells while retaining the integrity of the important surrounding physiological structures. It is suitable for patients with renal cell carcinoma who cannot be surgically resected or who do not want surgical resection, and can ensure the best postoperative renal function to the greatest extent, and has advantages that other thermal ablation treatments do not have. However, since irreversible electroporation therapy has high requirements for electrode needles and parameter settings, improper operation will directly affect the prognosis of patients. In order to improve the level of comprehensive treatment of renal cell cancer and standardize the operation technique of irreversible electroporation for renal cell carcinoma, the Committee of interventional minimally invasive therapy of the Chinese Medical Education Association took the lead in formulating the Expert Recommendation on image-guided irreversible electroporation ablation for Renal Cancer (2022 edition). The article introduces in detail the indications, contraindications, perioperative preparation, basic principles of operation, complications and related management and follow-up of irreversible electroporation for renal cell carcinoma, in order to provide reference for clinical practice.
不可逆电穿孔消融治疗可破坏肿瘤细胞，同时保留周围重要生理结构的完整性。它适用于无法进行手术切除或不愿接受手术切除的肾细胞癌患者，能在最大程度上确保术后肾功能最佳，具有其他热消融治疗所没有的优势。然而，由于不可逆电穿孔治疗对电极针和参数设置要求较高，操作不当将直接影响患者预后。为提高肾细胞癌综合治疗水平，规范肾细胞癌不可逆电穿孔的手术操作技术，中国医学教育协会介入微创治疗专业委员会牵头制定了《肾癌影像引导不可逆电穿孔消融专家推荐意见（2022版）》。文章详细介绍了肾细胞癌不可逆电穿孔的适应证、禁忌证、围手术期准备、手术基本原则、并发症及相关处理和随访等内容，以供临床实践参考。
