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[自身免疫性脑炎——重症医疗中的挑战与管理]

[Autoimmune encephalitis-Challenges and management in intensive medical care].

作者信息

Brämer Dirk, Geis Christian, Günther Albrecht

机构信息

Klinik für Neurologie, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Deutschland.

出版信息

Nervenarzt. 2023 Feb;94(2):113-119. doi: 10.1007/s00115-022-01423-x. Epub 2023 Jan 18.

Abstract

Despite relevant improvements in the diagnostics and treatment of autoimmune encephalitis (AE), severely affected patients still need treatment on the intensive care unit (ICU). Such complex disease states are sometimes difficult to bring under control and ICU complications have a negative influence on the outcome of treatment. A rapid diagnosis and timely initiation of immunotherapy are crucial to minimize ICU treatment and to avoid potentially severe complications. This article outlines the ICU treatment of autoimmune encephalitis and describes the most common challenges and complications of (neuro)intensive medical care and their management.

摘要

尽管自身免疫性脑炎(AE)的诊断和治疗有了相关进展,但病情严重的患者仍需要在重症监护病房(ICU)接受治疗。这种复杂的疾病状态有时难以控制,ICU并发症会对治疗结果产生负面影响。快速诊断并及时开始免疫治疗对于减少ICU治疗时间和避免潜在的严重并发症至关重要。本文概述了自身免疫性脑炎的ICU治疗,并描述了(神经)重症医疗中最常见的挑战和并发症及其管理方法。

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