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中年男性连贯感与死亡率的长期变化:一项基于人群的随访研究。

Long-term changes in sense of coherence and mortality among middle-aged men: A population -based follow-up study.

作者信息

Piiroinen Ilkka, Tuomainen Tomi-Pekka, Tolmunen Tommi, Kauhanen Jussi, Kurl Sudhir, Nilsen Charlotta, Suominen Sakari, Välimäki Tarja, Voutilainen Ari

机构信息

Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Finland.

Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Finland.

出版信息

Adv Life Course Res. 2022 Sep;53:100494. doi: 10.1016/j.alcr.2022.100494. Epub 2022 Jun 22.

Abstract

Sense of coherence (SOC) scale measures one's orientation to life. SOC is the core construct in Antonovsky's salutogenic model of health. It has been shown that weak SOC correlates with poor perceived health, low quality of life, and increased mortality. Some studies have indicated that SOC is not stable across life, but there are no previous studies on how a change of SOC is reflected in mortality. However, there is some evidence that a change in perceived quality of life is associated with mortality. The study explores the association between the change in SOC and mortality using longitudinal data from a cohort of middle-aged Finnish men recruited between 1986 and 1989. Approximately 11 years after the baseline examinations, between 1998 and 2001, 854 men returned the SOC questionnaire a second time. The baseline SOC was adjusted for the regression to the mean phenomenon between the two measurements. The hazard ratios of the SOC difference scores were adjusted for initial SOC age and 12 somatic risk factors of mortality (alcohol consumption, blood pressure, body mass index, cholesterol concentration, physical activity, education, smoking, marital status, employment status, history of cancer, history of cardiovascular disease and diabetes). SOC was not stable among middle-aged Finnish men and a decline in SOC was associated with an increased hazard of all-cause mortality. In the fully adjusted model, a decrease of one standard deviation (SD) of the SOC mean difference increased the mortality hazard by about 35 %, two SDs decrease about 70 %, and 2.5 SDs about 100 %. Strengthening SOC showed a limited association with decreasing mortality hazards in the age-adjusted model. Policies, strategies, or plans, supporting SOC in the middle-age may help to decrease mortality and increase quality of life in later years.

摘要

连贯感(SOC)量表用于衡量一个人的生活取向。连贯感是安托诺夫斯基健康促进模型的核心概念。研究表明,连贯感薄弱与健康感知差、生活质量低和死亡率上升相关。一些研究表明,连贯感在一生中并不稳定,但此前尚无关于连贯感变化如何反映在死亡率上的研究。然而,有证据表明,生活质量感知的变化与死亡率有关。本研究利用1986年至1989年间招募的一组芬兰中年男性的纵向数据,探讨连贯感变化与死亡率之间的关联。在基线检查约11年后,即1998年至2001年期间,854名男性再次返回了连贯感问卷。对基线连贯感进行了调整,以消除两次测量之间的均值回归现象。连贯感差异得分的风险比针对初始连贯感年龄和12种导致死亡的躯体风险因素(饮酒、血压、体重指数、胆固醇浓度、身体活动、教育程度、吸烟、婚姻状况、就业状况、癌症病史、心血管疾病病史和糖尿病)进行了调整。连贯感在芬兰中年男性中并不稳定,连贯感下降与全因死亡率风险增加相关。在完全调整模型中,连贯感平均差异降低一个标准差(SD)会使死亡风险增加约35%,降低两个标准差约70%,降低2.5个标准差约100%。在年龄调整模型中,增强连贯感与降低死亡风险的关联有限。在中年时期支持连贯感的政策、策略或计划可能有助于降低死亡率并提高晚年生活质量。

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