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眼前节光学相干断层扫描和超声生物显微镜检查在诊断酷似结节性巩膜炎的结膜下真菌病中的应用

Anterior segment optical coherence tomography and ultrasound biomicroscopy in the diagnosis of subconjunctival mycosis mimicking nodular scleritis.

作者信息

Vishwakarma Pratima, Murthy Somasheila I, Joshi Vineet, Mishra Dilip Kumar

机构信息

Shantilal Shangvi Cornea Institute, LV Prasad Eye Institute, Hyderabad, India.

Shantilal Shangvi Cornea Institute, LV Prasad Eye Institute, Hyderabad, India

出版信息

BMJ Case Rep. 2023 Jan 17;16(1):e253924. doi: 10.1136/bcr-2022-253924.

Abstract

A female patient in her 20s presented with a bulbar conjunctival mass lesion that was diagnosed as nodular scleritis. It was treated with topical and oral steroids in another hospital. Imaging was done using anterior segment optical coherence tomography and ultrasound biomicroscopy, which helped to rule out scleritis and subconjunctival cysticercosis. Histopathology of the excision biopsy specimen revealed fungal filaments. Topical antifungals were started, and the condition resolved without recurrence after therapy. Although rare, infections should be considered in the differential diagnosis of conjunctival mass lesions. Imaging can help to rule out other entities and guide towards appropriate management.

摘要

一名20多岁的女性患者出现球结膜肿物病变,被诊断为结节性巩膜炎。在另一家医院接受了局部和口服类固醇治疗。使用眼前节光学相干断层扫描和超声生物显微镜进行了影像学检查,这有助于排除巩膜炎和结膜下囊尾蚴病。切除活检标本的组织病理学显示有真菌丝。开始使用局部抗真菌药物治疗,治疗后病情缓解且未复发。尽管罕见,但在结膜肿物病变的鉴别诊断中应考虑感染因素。影像学检查有助于排除其他疾病并指导进行适当的治疗。

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本文引用的文献

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Cysticercosis of the eye.眼部囊尾蚴病
Int J Ophthalmol. 2017 Aug 18;10(8):1319-1324. doi: 10.18240/ijo.2017.08.21. eCollection 2017.
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Management of conjunctival malignant melanoma: a review and update.结膜恶性黑色素瘤的管理:综述与更新
Expert Rev Ophthalmol. 2014 Jun;9(3):185-204. doi: 10.1586/17469899.2014.921119.
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Dematiaceous fungi mimicking a conjunctival melanoma.拟似眼黑色素瘤的有隔真菌。
Ophthalmic Plast Reconstr Surg. 2013 Mar-Apr;29(2):e65-6. doi: 10.1097/IOP.0b013e31826c2fd7.
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Chromoblastomycosis of the conjunctiva mimicking melanoma of the ciliary body.
Arch Ophthalmol. 2012 Dec;130(12):1615-7. doi: 10.1001/archophthalmol.2012.1573.

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